ArticleJournal of oral microbiology2022
Maturation of the oral microbiota during primary teeth eruption: a longitudinal, preliminary study.
Article in Journal of oral microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Systematic analyses uncover robust salivary microbial signatures and host-microbiome perturbations in oral squamous cell carcinoma.mSystems · 2025Pooled it
- Association of Breastfeeding and Early Childhood Caries: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Exploring Oral Microbiome in Healthy Infants and Children: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Modulating Oral Microbiota to Prevent Dental Caries: A Microbial Ecology Approach.Dentistry journal · 2026Review
- Does permanent tooth eruption introduce periodontal pathogens? A preliminary study.Odontology · 2026Article
- Concentrations of selected human milk components influence the infant oral microbiome to a greater degree than estimated intakes.Frontiers in cellular and infection microbiology · 2026Article
- The Infant Oral Microbiome: Developmental Dynamics, Modulating Factors, and Implications for Oral and Systemic Health.International journal of molecular sciences · 2025Review
- Cytotoxic and antifungal effects of different teething oral gels: an in-vitro study.Head & face medicine · 2025Article
- Effect of implant abutment surface treatments on bacterial biofilm composition and structure.Journal of oral microbiology · 2025Article
- Acquisition of the Oral Microbiome.Advances in experimental medicine and biology · 2025Review
- Characterization of oral microbiota in 6-8-month-old small breed dogs.BMC veterinary research · 2024Article
- Construction of a caries diagnosis model based on microbiome novelty score.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2023Article
- Impact of breastfeeding and other early-life factors on the development of the oral microbiome.Frontiers in microbiology · 2023Review
- Oral microbiota dysbiosis accelerates the development and onset of mucositis and oral ulcers.Frontiers in microbiology · 2023Review
- Microbiota of preterm infant develops over time along with the first teeth eruption.Frontiers in microbiology · 2022Article
- The dynamic communities of oral microbiome in neonates.Frontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Oral microbiota that established in the early years of life may influence the child's oral health in the long term. Until now, no consensus is reached about whether the development of the oral microbiota is more related with age increase or more with teeth eruption. Objective: To analyze the microbiota development of both saliva and supragingival plaque during the gradual eruption of primary teeth in caries-free infants and toddlers. Methods: Saliva and plaque samples were collected at five and four dentition states, respectively, and were identified by bacterial Results: During the longitudinal observation, the saliva ecosystem seemed more complex and dynamic than the plaque, with larger bacteria quantity and more significantly varied species over time. About 70% of the initial colonized OTUs in plaque persisted until the completion of the primary dentition. Transient bacteria were mostly detected in the early saliva and plaque microbiota, which came from the environment and other sites of the human body. Microbial diversity in both saliva and plaque varied greatly from pre-dentition to full eruption of eight anterior teeth, but not during the eruption of primary molars. Conclusion: Oral bacterial development follows an ordered sequence during the primary teeth eruption. 'Fully eruption of all primary anterior teeth' is a critical stage in this process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.