Evidence map›Paper›PMID 35309306›Full record

ReviewFrontiers in immunology2022

Epigenetic Control of Regulatory T Cell Stability and Function: Implications for Translation.

Anthony M Joudi, Carla P Reyes Flores, Benjamin D Singer

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Role of Epigenetic Modifications in The Aberrant Expression of TheInternational journal of fertility & sterility · 2026
    Article
  6. Review
  7. Article
  8. International journal of molecular sciences · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. The emerging role of T cells in depression.Frontiers in psychiatry · 2026
    Review
  16. Review
  17. Review
  18. Article
  19. Regulatory T cell memory: implications for malaria.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anthony M JoudiDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Carla P Reyes FloresDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Benjamin D SingerDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Tissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GR Scott Budinger · 2015 to 2026
$26.9M
Technology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LUIS A. Nunes AMARAL · 2018 to 2026
$24.7M
The Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9M
Training Program In Lung SciencesT32HL076139 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE, Jacob I Sznajder · 2004 to 2026
$9.6M
Mechanisms of regulatory T cell-mediated recovery from severe viral pneumoniaR01HL149883 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Benjamin David Singer · 2020 to 2026
$4.1M
The role of epigenetic regulator UHRF1 in stability of induced regulatory T-cell function during influenza A virus-induced lung injuryF32HL162418 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JOUDI, ANTHONY · 2022 to 2025
$251k
Epigenetic modifiers of regulatory T cell function following viral pneumoniaR01HL153122 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SINGER, BENJAMIN DAVID · 2021 to 2021
$63k
NCATS NIH HHS UL1 TR001422NHLBI NIH HHS F32 HL162418NHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL149883NHLBI NIH HHS R01 HL153122NHLBI NIH HHS T32 HL076139NIAID NIH HHS U19 AI135964NIA NIH HHS P01 AG049665
6 · The paper itself

Abstract

FoxP3

Indexed as

Forkhead Transcription FactorsT-Lymphocytes, RegulatoryCell DifferentiationEpigenesis, GeneticSelf ToleranceForkhead Transcription FactorsDNA methylationepigeneticsinflammationplasticityregulatory T cellstherapeutics

Identifiers

PMID35309306
PMCPMC8924620
OpenAlexW4214951940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.