Evidence map›Paper›PMID 35309224›Full record

ReviewFrontiers in public health2022

Accelerating the Development of Measles and Rubella Microarray Patches to Eliminate Measles and Rubella: Recent Progress, Remaining Challenges.

Mateusz Hasso-Agopsowicz, Natasha Crowcroft, Robin Biellik, Christopher J Gregory, Marion Menozzi-Arnaud, Jean-Pierre Amorij, Philippe-Alexandre Gilbert, Kristen Earle, Collrane Frivold, Courtney Jarrahian and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Mateusz Hasso-AgopsowiczImmunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland.
Natasha CrowcroftImmunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland.
Robin BiellikIndependent, La Rippe, Switzerland.
Christopher J GregoryImmunization Unit, Programme Division, United Nations Children's Fund (UNICEF), New York, NY, United States.
Marion Menozzi-ArnaudGavi, The Vaccine Alliance, Geneva, Switzerland.
Jean-Pierre AmorijSupply Division, Vaccine Centre, UNICEF, Copenhagen, Denmark.
Philippe-Alexandre GilbertVaccine Development and Surveillance, Bill and Melinda Gates Foundation, Seattle, WA, United States.
Kristen EarleVaccine Development and Surveillance, Bill and Melinda Gates Foundation, Seattle, WA, United States.
Collrane FrivoldMedical Devices and Health Technologies, PATH, Seattle, WA, United States.
Courtney JarrahianMedical Devices and Health Technologies, PATH, Seattle, WA, United States.
Mercy MvunduraMedical Devices and Health Technologies, PATH, Seattle, WA, United States.
Jessica J MistilisMedical Devices and Health Technologies, PATH, Seattle, WA, United States.
David N DurrheimMedicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.
Birgitte GiersingImmunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland.
World Health Organization · CHBill & Melinda Gates Foundation · USGavi · CHUnited Nations Children's Fund · USUniversity of Newcastle Australia · AU

Funding

World Health Organization 001
6 · The paper itself

Abstract

Measles and rubella microarray patches (MR-MAPs) are critical in achieving measles and rubella eradication, a goal highly unlikely to meet with current vaccines presentations. With low commercial incentive to MAP developers, limited and uncertain funding, the need for investment in a novel manufacturing facility, and remaining questions about the source of antigen, product demand, and regulatory pathway, MR-MAPs are unlikely to be prequalified by WHO and ready for use before 2033. This article describes the current progress of MR-MAPs, highlights challenges and opportunities pertinent to MR-MAPs manufacturing, regulatory approval, creating demand, and timelines to licensure. It also describes activities that are being undertaken by multiple partners to incentivise investment in and accelerate the development of MR-MAPs.

Indexed as

MeaslesRubellaHumansMeasles VaccineRubella VaccineMeasles VaccineRubella Vaccineinnovationmeaslesmicroarray patchesrubellavaccine

Identifiers

PMID35309224
PMCPMC8924450
OpenAlexW4214890236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.