SynthesisFrontiers in public health2022
Impact of Polypharmacy, Drug-Related Problems, and Potentially Inappropriate Medications in Geriatric Patients and Its Implications for Bulgaria-Narrative Review and Meta-Analysis.
Synthesis in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Association of polypharmacy and perioperative outcomes: Systematic review and meta-analysis.Journal of perioperative practicePooled it
- Restarting Medications After Deprescribing in Adults Discharged From Hospital to Skilled Nursing.JAMA network open · 2026Article
- Home medication review and drug-related problems in patients with chronic diseases at primary health centers in Yogyakarta, Indonesia: A cross-sectional multicenter study.Belitung nursing journal · 2026Article
- Potentially inappropriate medications and regimen complexity among elderly patients in the emergency department: Insights from a pharmacist-led medication reconciliation study.Qatar medical journal · 2026Article
- Drug-related problems and their determinants among stroke patients in suburban China: a PCNE-based analysis with targeted initiatives.Frontiers in public health · 2026Article
- Review
- Prevalence and factors with potentially inappropriate prescribing among older outpatients with depression: a multicentre study across China.Journal of global health · 2025Observational
- Trends of potentially inappropriate prescribing among older outpatients in China between 2015-21.Journal of global health · 2025Article
- Potentially Inappropriate Medication Use Among Older Adults with Cognitive Impairment and Dementia Attending Primary Care-Based Memory Clinics.Pharmacy (Basel, Switzerland) · 2025Article
- Prevalence and Factors with Potentially Inappropriate Prescribing among Older Surgical Outpatients in China: A Nationwide Cross-sectional Study in 100 Hospitals.Journal of epidemiology and global health · 2025Article
- Impact of Chinese criteria on potentially inappropriate medication use in China.Journal of global health · 2025Article
- Polypharmacy, drug-drug interactions and adverse drug reactions in older Chinese cancer patients: evidence from CHARLS.Frontiers in pharmacology · 2025Article
- Analysis of the level of polypharmacy in patients from an isolated rural area: effect of age, sex, and chronic diseases.Frontiers in digital health · 2025Article
- Adverse drug reactions and drug-related problems with supportive care medications among the oncological population.Discover oncology · 2024Article
- Food Supplements and Their Use in Elderly Subjects-Challenges and Risks in Selected Health Issues: A Narrative Review.Foods (Basel, Switzerland) · 2024Review
- Prevalence, country-specific prescribing patterns and determinants of benzodiazepine use in community-residing older adults in 7 European countries.BMC geriatrics · 2024Article
- Drug-related problems among type 2 diabetic patients in Sunwal Municipality of Western Nepal.PloS one · 2024Article
- Evaluation of medication safety assessment tools for pharmacist-led medication reviews: the Eastern European pilot project.Frontiers in pharmacology · 2024Article
- Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic.BMC geriatrics · 2023Article
- Potentially inappropriate medication use as predictors of hospitalization for residents in nursing home.BMC geriatrics · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Polypharmacy and inappropriate prescribing are overlooked issues in Bulgaria. We aimed at collecting and analyzing global literature on the most prevalent risk factors and investigating what they could reveal about current practice. Materials and Methods: A systematic narrative review and meta-analysis was conducted on the topic, investigating the prevalence of polypharmacy, odds of potentially inappropriate medications (PIMs) due to polypharmacy, and the likelihood of developing a drug-related problem (DRP) due to PIMs. The results were then related to current demographic statistics to estimate the potential impact on Bulgarian elderly patients. Results: The prevalence of polypharmacy was estimated at 41% in elderly populations. The odds of a potentially inappropriate medication being prescribed were 2.095, with an expected 30.84% of those leading to a DRP. These numbers indicated that the expected Bulgarian elderly with polypharmacy should be 709,676 with 212,903 cases of DRPs. Conclusion: Global polypharmacy rates seem to be on the rise, with an expected increase in DRPs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.