Evidence map›Paper›PMID 35309120›Full record

ArticleFrontiers in genetics2022

Transcriptome Sequencing-Based Mining of Genes Associated With Pubertal Initiation in Dolang Sheep.

Zhishuai Zhang, Zhiyuan Sui, Jihu Zhang, Qingjin Li, Yongjie Zhang, Feng Xing

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhishuai ZhangKey Laboratory of Tarim Animal Husbandry Science and Technology, Xinjang Production and Construction Group, College of Animal Science, Tarim University, Alaer, China.
Zhiyuan SuiKey Laboratory of Tarim Animal Husbandry Science and Technology, Xinjang Production and Construction Group, College of Animal Science, Tarim University, Alaer, China.
Jihu ZhangKey Laboratory of Tarim Animal Husbandry Science and Technology, Xinjang Production and Construction Group, College of Animal Science, Tarim University, Alaer, China.
Qingjin LiKey Laboratory of Tarim Animal Husbandry Science and Technology, Xinjang Production and Construction Group, College of Animal Science, Tarim University, Alaer, China.
Yongjie ZhangKey Laboratory of Tarim Animal Husbandry Science and Technology, Xinjang Production and Construction Group, College of Animal Science, Tarim University, Alaer, China.
Feng XingKey Laboratory of Tarim Animal Husbandry Science and Technology, Xinjang Production and Construction Group, College of Animal Science, Tarim University, Alaer, China.
Tarim University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improving the fertility of sheep is an important goal in sheep breeding as it greatly increases the productivity. Dolang sheep is a typical representative breed of lamb in Xinjiang and is the main local sheep breed and meat source in the region. To explore the genes associated with the initiation of puberty in Dolang sheep, the hypothalamic tissues of Dolang sheep prepubertal, pubertal, and postpubertal periods were collected for RNA-seq analysis on the Illumina platform, generating 64.08 Gb clean reads. A total of 575, 166, and 648 differentially expressed genes (DEGs) were detected in prepuberty_vs._puberty, postpuberty_vs._prepuberty, and postpuberty_vs._puberty analyses, respectively. Based on Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses, the related genes involved in the initiation of puberty in Dolang sheep were mined. Ten genes that have direct or indirect functions in the initiation of puberty in Dolang sheep were screened using the GO and KEGG results. Additionally, quantitative real-time PCR was used to verify the reliability of the RNA-Seq data. This study provided a new approach for revealing the mechanism of puberty initiation in sheep and provided a theoretical basis and candidate genes for the breeding of early-pubertal sheep by molecular techniques, and at the same time, it is also beneficial for the protection, development, and utilization of the fine genetic resources of Xinjiang local sheep.

Indexed as

differential gene expressionDolang sheephypothalamuspuberty initiationRNA-seq

Identifiers

PMID35309120
PMCPMC8928774
OpenAlexW4214829738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.