Evidence map›Paper›PMID 35309073›Full record

ArticleFrontiers in physiology2022

Dietary Administration of L-Carnitine During the Fattening Period of Early Feed Restricted Lambs Modifies Ruminal Fermentation but Does Not Improve Feed Efficiency.

Alba Martín, F Javier Giráldez, Paola Cremonesi, Bianca Castiglioni, Filippo Biscarini, Fabrizio Ceciliani, Nuria Santos, Sonia Andrés

Abstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Thymol modulates rumen barrier function and inflammation in feed-restricted lambs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Gut microbiota and meat quality.Frontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alba MartínDepartment of Nutrition and Production of Herbivores, Instituto de Ganadería de Montaña, CSIC-Universidad de León, León, Spain.
F Javier GiráldezDepartment of Nutrition and Production of Herbivores, Instituto de Ganadería de Montaña, CSIC-Universidad de León, León, Spain.
Paola CremonesiInstitute of Agricultural Biology and Biotechnology, Italian National Research Council, Lodi, Italy.
Bianca CastiglioniInstitute of Agricultural Biology and Biotechnology, Italian National Research Council, Lodi, Italy.
Filippo BiscariniInstitute of Agricultural Biology and Biotechnology, Italian National Research Council, Lodi, Italy.
Fabrizio CecilianiDepartment of Veterinary Medicine, Università degli Studi di Milano, Milano, Italy.
Nuria SantosDepartment of Nutrition and Production of Herbivores, Instituto de Ganadería de Montaña, CSIC-Universidad de León, León, Spain.
Sonia AndrésDepartment of Nutrition and Production of Herbivores, Instituto de Ganadería de Montaña, CSIC-Universidad de León, León, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early feed restriction of lambs may program animals to achieve reduced feed efficiency traits as a consequence of permanent mitochondrial dysfunction. The hypothesis at the background of the present study is that dietary administration of L-Carnitine (a compound that promotes the activation and transportation of fatty acids into the mitochondria) during the fattening period of early feed restricted lambs can: (a) improve the biochemical profile of early feed restricted lambs, (b) improve feed efficiency, (c) modulate the ruminal and intestinal microbiota, and (d) induce changes in the gastrointestinal mucosa, including the immune status. Twenty-two newborn male Merino lambs were raised under natural conditions but separated from the dams for 9 h daily to allow feed restriction during the suckling period. At weaning, lambs were assigned to a control group being fed

Indexed as

feed efficiencyfeed restrictionlambL-Carnitinemicrobiotanutritional programmingresidual feed intakeruminal fermentation

Identifiers

PMID35309073
PMCPMC8929275

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.