Evidence map›Paper›PMID 35309059›Full record

ArticleFrontiers in physiology2022

Extended ECG Improves Classification of Paroxysmal and Persistent Atrial Fibrillation Based on P- and f-Waves.

Matthias Daniel Zink, Rita Laureanti, Ben J M Hermans, Laurent Pison, Sander Verheule, Suzanne Philippens, Nikki Pluymaekers, Mindy Vroomen, Astrid Hermans, Arne van Hunnik and 7 more

Abstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Histological evaluation of clinically defined atrial cardiomyopathy stages and their association with atrial fibrillation burden under continuous monitoring for a 2.5-year follow-up.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Atrial cardiomyopathy revisited-evolution of a concept: a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS).Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Matthias Daniel ZinkRWTH University Hospital Aachen, Internal Medicine I, Cardiology and Vascular Medicine, Aachen, Germany.
Rita LaureantiDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.
Ben J M HermansCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Laurent PisonCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Sander VerheuleCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Suzanne PhilippensDepartment of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht, Netherlands.
Nikki PluymaekersCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Mindy VroomenCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Astrid HermansCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Arne van HunnikCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Harry J G M CrijnsCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Kevin VernooyCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Dominik LinzCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Luca MainardiDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.
Angelo AuricchioCenter for Computational Modeling in Cardiology, Lugano, Switzerland.
Stef ZeemeringCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.
Ulrich SchottenCardiovascular Research Institute Maastricht (CARIM), Physiology, Maastricht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The standard 12-lead ECG has been shown to be of value in characterizing atrial conduction properties. The added value of extended ECG recordings (longer recordings from more sites) has not been systematically explored yet. Objective: The aim of this study is to employ an extended ECG to identify characteristics of atrial electrical activity related to paroxysmal vs. persistent atrial fibrillation (AF). Methods: In 247 participants scheduled for AF ablation, an extended ECG was recorded (12 standard plus 3 additional leads, 5 min recording, no filtering). For patients presenting in sinus rhythm (SR), the signal-averaged P-wave and the spatiotemporal P-wave variability was analyzed. For patients presenting in AF, f-wave properties in the QRST (the amplitude complex of the ventricular electrical activity: Q-, R-, S-, and T-wave)-canceled ECG were determined. Results: Significant differences between paroxysmal ( Conclusion: The P- and f-wave analysis of extended ECG configurations identified specific ECG features allowing improved classification of paroxysmal vs. persistent AF. The extended ECG significantly improved AF-type classification in our analyzed data as compared to a standard 10-s 12-lead ECG. Whether this can result in a better clinical AF type classification warrants further prospective study.

Indexed as

atrial fibrillationf-waveparoxysmalpersistentP-waveP-wave variabilityQRST-canceled ECGsignal-averaged P-wave

Identifiers

PMID35309059
PMCPMC8931504

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.