Evidence map›Paper›PMID 35309036›Full record

ArticleERJ open research2022

Reliability of translaryngeal airway resistance measurements during maximal exercise.

Zoe Fretheim-Kelly, Mette Engan, Hege Clemm, Tiina Andersen, John-Helge Heimdal, Eric Strand, Thomas Halvorsen, Ola Røksund, Maria Vollsæter

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zoe Fretheim-KellyFaculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.ORCID https://orcid.org/0000-0003-2402-195X
Mette EnganDept of Paediatrics and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.
Hege ClemmDept of Paediatrics and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.ORCID https://orcid.org/0000-0002-0096-4032
Tiina AndersenNorwegian Advisory Unit on Home Mechanical Ventilation, Thoracic Dept, Haukeland University Hospital, Bergen, Norway.
John-Helge HeimdalDept of Surgery, University of Bergen, Bergen, Norway.
Eric StrandFaculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.
Thomas HalvorsenDept of Clinical Science, University of Bergen, Bergen, Norway.ORCID https://orcid.org/0000-0003-1471-0225
Ola RøksundDept of Paediatrics and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.
Maria VollsæterDept of Paediatrics and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.
Haukeland University Hospital · NOUniversity of Bergen · NONorwegian University of Life Sciences · NOWestern Norway University of Applied Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Exercise-induced laryngeal obstruction is an important cause of exertional dyspnoea. The diagnosis rests on visual judgement of relative changes of the laryngeal inlet during continuous laryngoscopy exercise (CLE) tests, but we lack objective measures that reflect functional consequences. We aimed to investigate repeatability and normal values of translaryngeal airway resistance measured at maximal intensity exercise. Methods: 31 healthy nonsmokers without exercise-related breathing problems were recruited. Participants performed two CLE tests with verified positioning of two pressure sensors, one at the tip of the epiglottis (supraglottic) and one by the fifth tracheal ring (subglottic). Airway pressure and flow data were continuously collected breath-by-breath and used to calculate translaryngeal resistance at peak exercise. Laryngeal obstruction was assessed according to a standardised CLE score system. Results: Data from 26 participants (16 females) with two successful tests and equal CLE scores on both test sessions were included in the translaryngeal resistance repeatability analyses. The coefficient of repeatability (CR) was 0.62 cmH Conclusions: This study establishes translaryngeal airway resistance obtained during exercise as a reliable parameter in respiratory medicine, opening the door for more informed treatment decisions and future research on the role of the larynx in health and disease.

Identifiers

PMID35309036
PMCPMC8923134
OpenAlexW4213133891

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.