Evidence map›Paper›PMID 35308759›Full record

ArticleCureus2022

Evaluation of Safety for Scanning Carbon-Ion Radiotherapy in Hemodialysis Patients With Prostate Cancer.

Yosuke Takakusagi, Makito Suga, Yohsuke Kusano, Kio Kano, Satoshi Shima, Keisuke Tsuchida, Nobutaka Mizoguchi, Itsuko Serizawa, Daisaku Yoshida, Tadashi Kamada and 2 more

Abstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yosuke TakakusagiDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.
Makito SugaDivision of Radiation Therapy Technology, Kanagawa Cancer Center, Yokohama, JPN.
Yohsuke KusanoSection of Medical Physics and Engineering, Kanagawa Cancer Center, Yokohama, JPN.
Kio KanoDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.
Satoshi ShimaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.
Keisuke TsuchidaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.
Nobutaka MizoguchiDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.
Itsuko SerizawaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.
Daisaku YoshidaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.
Tadashi KamadaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.
Shinichi MinoharaSection of Medical Physics and Engineering, Kanagawa Cancer Center, Yokohama, JPN.
Hiroyuki KatohDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aim The efficacy and safety of carbon-ion radiotherapy (CIRT) for prostate cancer have already been demonstrated. The number of hemodialysis (HD) patients is increasing. Although the toxicity of CIRT in HD patients may be more severe, it has been insufficiently investigated. Therefore, we retrospectively analyzed the safety of CIRT for HD patients with prostate cancer in the present study. Materials and methods Five HD patients with prostate cancer who underwent CIRT at the Kanagawa Cancer Center during November 2015-2020 were included in this study. CIRT was delivered by the raster scanning method (sCIRT). Adverse events were assessed using the Common Terminology Criteria for Adverse Events version 5.0. The dose-volume histogram (DVH) parameters of the target volume and normal organs were evaluated between initial planning computed tomography (CT) and in-room CT images. Results In the acute phase, Grade 1 genitourinary toxicity was recorded in one patient. In the late phase, Grade 1 genitourinary toxicity was recorded in two patients. No gastrointestinal toxicities were noted during the follow-up period. In-room CT analysis revealed no significant differences among all DVH parameters of the target volume and normal organs when compared with the treatment plan dose. Conclusions The safety of sCIRT for prostate cancer in HD patients was investigated in the present study. In-room CT analysis suggested the robustness of the treatment plan. According to the present results, sCIRT for prostate cancer can be safely performed in HD patients.

Indexed as

carbon-ion radiotherapyhemodialysisin-room ctprostate cancersafety

Identifiers

PMID35308759
PMCPMC8925932

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.