ArticleRoyal Society open science2022
The HEV Ventilator: at the interface between particle physics and biomedical engineering.
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Article in Royal Society open science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Testing of pandemic ventilators under early and agile development.Frontiers in medical technology · 2022Article
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Authors and funding
91 authors at 20 institutions in 14 countries.
Jan BuytaertEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0002-7958-6790
Paula CollinsEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0003-1437-4022
Adam Abed AbudEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0002-2788-3822
Phil AllportParticle Physics Group, School of Physics and Astronomy, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0001-7303-2570
Antonio Pazos ÁlvarezInstituto Galego de Física de Altas Enerxías (IGFAE), Universidade de Santiago de Compostela, Santiago de Compostela, 15782 Galicia, Spain.ORCID 0000-0003-3153-8084
Kazuyoshi AkibaNikhef National Institute for Subatomic Physics, Amsterdam 1098 XG, The Netherlands.ORCID 0000-0002-6736-471X
Oscar Augusto de Aguiar FranciscoEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0003-2735-678X
Aurelio BayInstitute of Physics, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.ORCID 0000-0002-4862-9399
Florian BernardInstitute of Physics, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Sophie BaronEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0003-2717-6017
Claudia BertellaEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0002-3160-147X
Josef X BrunnerNeosim AG, CH-7000 Chur, Switzerland.ORCID 0000-0001-8460-6197
Themis BowcockOliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE, UK.ORCID 0000-0002-3505-6915
Martine Buytaert-De JodeEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Wiktor ByczynskiEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Ricardo De CarvalhoHôpitaux Universitaires de Genève, 1205 Genève, Switzerland.
Victor CocoEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0002-5310-6808
Ruth CollinsDepartment of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-7513-2038
Nikola DikicApplied Physics Laboratory, Faculty of Electronic Engineering, University of Nis˘, Aleksandra Medvedeva 14, Nis˘ 18000, Serbia.ORCID 0000-0002-2489-9204
Nicolas DousseHôpitaux Universitaires de Genève, 1205 Genève, Switzerland.
Bruce DowdPrince of Wales Hospital, Randwick, New South Wales 2052, Australia.
Kārlis DreimanisCentre of High-Energy Physics and Accelerator Technologies and Faculty of Computer Science and Information Technology, Riga Technical University, 1 Kalku Street, Riga LV-1658, Latvia.ORCID 0000-0003-0972-5641
Raphael DumpsEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Paolo DuranteEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Walid FadelEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Stephen FarryOliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE, UK.ORCID 0000-0001-5119-9740
Antonio Fernàndez PrietoInstituto Galego de Física de Altas Enerxías (IGFAE), Universidade de Santiago de Compostela, Santiago de Compostela, 15782 Galicia, Spain.ORCID 0000-0003-1984-6367
Arturo Fernàndez TèllezFacultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico.ORCID 0000-0003-0152-4220
Gordon FlynnPrince of Wales Hospital, Randwick, New South Wales 2052, Australia.
Vinicius Franco LimaOliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE, UK.
Raymond FreiInstitute of Physics, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Abraham Gallas TorreiraInstituto Galego de Física de Altas Enerxías (IGFAE), Universidade de Santiago de Compostela, Santiago de Compostela, 15782 Galicia, Spain.ORCID 0000-0002-2745-7954
Tonatiuh García ChàvezFacultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico.ORCID 0000-0002-6224-1577
Evangelos GazisNational Technical University of Athens - NTUA, Zografou Campus, 15780 Athens, Greece.ORCID 0000-0002-9272-4254
Roberto GuidaEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0001-8413-9672
Karol HennessyOliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE, UK.ORCID 0000-0002-1529-8087
Andre HenriquesEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0003-1521-3423
David HutchcroftOliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE, UK.ORCID 0000-0002-4174-6509
Stefan IlicApplied Physics Laboratory, Faculty of Electronic Engineering, University of Nis˘, Aleksandra Medvedeva 14, Nis˘ 18000, Serbia.ORCID 0000-0002-1721-9039
Artūrs IvanovsCentre of High-Energy Physics and Accelerator Technologies and Faculty of Computer Science and Information Technology, Riga Technical University, 1 Kalku Street, Riga LV-1658, Latvia.
Aleksandar JevticGZA Hospitals, 2018 Antwerp, Belgium.ORCID 0000-0001-7122-0324
Emigdio Jimenez DominguezFacultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico.ORCID 0000-0001-7702-8421
Christian JoramEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0001-6018-6001
Kacper KapusniakEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Edgar Lemos CidInstituto Galego de Física de Altas Enerxías (IGFAE), Universidade de Santiago de Compostela, Santiago de Compostela, 15782 Galicia, Spain.ORCID 0000-0003-3001-6268
Jana LindnerUniversity of Applied Sciences Offenburg, 77652 Offenburg, Baden-Wuerttemberg, Germany.
Rolf LindnerEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
M Ivàn Martínez HernàndezFacultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico.
Mirko MeboldtProduct Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0001-5828-5406
Marko MilovanovicEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0001-5828-5406
Sylvain MicoEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Johan MorantEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Michel MorelEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0001-5828-5406
Georg MännelFraunhofer Research Institution for Individualized and Cell-based Medical Engineering (IMTE), 23562 Lübeck, Germany.ORCID 0000-0003-3508-9052
Dónal MurrayDepartment of Physics and Astronomy, University of Manchester, Manchester M13 9PL, UK.
Irina NastevaUniversidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-972, Brazil.ORCID 0000-0001-7115-7214
Niko NeufeldEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0003-2298-0102
Igor NeuholdEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0001-7115-7214
Francisco Pardo-Sobrino LópezAnesthesiology-Reanimation and Pain Therapeutics Service, Lucus Augusti University Hospital, 27003 Lugo, Spain.
Eliseo Pèrez TrigoInstituto Galego de Física de Altas Enerxías (IGFAE), Universidade de Santiago de Compostela, Santiago de Compostela, 15782 Galicia, Spain.ORCID 0000-0001-7650-6639
Gonzalo Pichel JallasInstituto Galego de Física de Altas Enerxías (IGFAE), Universidade de Santiago de Compostela, Santiago de Compostela, 15782 Galicia, Spain.
Edyta PilorzEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Lise PiquilloudAdult Intensive Care Unit, University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-4226-8772
Xavier PonsEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
David ReinerJohn Curtin School of Medical Research, Canberra, Australian Capital Territory 2600, Australia.ORCID 0000-0001-6405-7389
Hector David Règules MedelFacultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico.ORCID 0000-0003-0119-3505
Saul Rodríguez RamírezFacultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico.ORCID 0000-0003-2864-8565
Mario Rodíguez CahuantziFacultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico.ORCID 0000-0002-9596-1060
Carl RoosensGZA Hospitals, 2018 Antwerp, Belgium.
Philipp RostalskiInstitute for Electrical Engineering in Medicine, University of Lübeck, 23562 Lübeck, Germany.ORCID 0000-0003-0326-168X
Freek SandersEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Eric SaucetHôpitaux Universitaires de Genève, 1205 Genève, Switzerland.
Marianne Schmid DanersProduct Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0002-6411-8871
Burkhard SchmidtEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Patrick SchoettkerCentre Hospitalier Universitaire Vaudois, Lausanne CH-1011, Switzerland.ORCID 0000-0001-5370-048X
Rainer SchwemmerEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Heinrich SchindlerEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Archana SharmaEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
Derick SivakumaranProduct Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0003-3312-1004
Christophe SigaudEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0001-6970-8187
Vasilios SpitasNational Technical University of Athens - NTUA, Zografou Campus, 15780 Athens, Greece.
Nicola SteffenProduct Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, 8092 Zurich, Switzerland.
Peter SvihraDepartment of Physics and Astronomy, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-7811-2147
Guillermo Tejeda MuñozFacultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico.ORCID 0000-0003-2184-3106
Nikolaos TachatosProduct Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0003-4261-3406
Efstratios TsolakisNational Technical University of Athens - NTUA, Zografou Campus, 15780 Athens, Greece.
Jan van LeemputGZA Hospitals, 2018 Antwerp, Belgium.ORCID 0000-0002-6482-0062
Laurence VignauxCardio-Respiratory Units, Hôpital de La Tour, 1217 Meyrin, Switzerland.
Francois VaseyEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.ORCID 0000-0002-4360-5259
Hamish WoontonMonash Health, Melbourne, Victoria 3168, Australia.
Ken WyllieEuropean Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland.
European Organization for Nuclear Research · CHBenemérita Universidad Autónoma de Puebla · MXUniversity of Liverpool · GBUniversidade de Santiago de Compostela · ESETH Zurich · CHÉcole Polytechnique Fédérale de Lausanne · CHGZA Ziekenhuizen Campus Sint-Augustinus · BEHôpital Beau-Séjour · CHNational Technical University of Athens · GRUniversity of Manchester · GBFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering · DERiga Technical University · LVUniversity of Nis · RSACT GovernmentCornell University · USCracow University of Technology · PLDeutsches Elektronen-Synchrotron DESY · DEHôpital de la Tour · CHHospital Universitario Lucus Augusti · ESMonash Health · AU
Funding
No grant is acknowledged in the PubMed record.
Abstract
A high-quality, low-cost ventilator, dubbed HEV, has been developed by the particle physics community working together with biomedical engineers and physicians around the world. The HEV design is suitable for use both in and out of hospital intensive care units, provides a variety of modes and is capable of supporting spontaneous breathing and supplying oxygen-enriched air. An external air supply can be combined with the unit for use in situations where compressed air is not readily available. HEV supports remote training and post market surveillance via a Web interface and data logging to complement standard touch screen operation, making it suitable for a wide range of geographical deployment. The HEV design places emphasis on the ventilation performance, especially the quality and accuracy of the pressure curves, reactivity of the trigger, measurement of delivered volume and control of oxygen mixing, delivering a global performance which will be applicable to ventilator needs beyond the COVID-19 pandemic. This article describes the conceptual design and presents the prototype units together with a performance evaluation.
Indexed as
COVID-19oxygen enrichmenttriggeringventilation modes
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