ReviewFrontiers in human neuroscience2022
A Predictive Coding Framework for Understanding Major Depression.
Review in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- The effects of coloring therapy on patients with generalized anxiety disorder.Animal models and experimental medicine · 2022Trial
- Effect of depression screening on future depressive symptoms in a persistent pain population: mediation analysis.Pain reports · 2026Article
- Brain rhythms of depression: A predictive processing perspective.Trends in neurosciences · 2026Review
- Mood modulations of emotional word processing: A predictive perspective view of EEG data.Cognitive, affective & behavioral neuroscience · 2026Article
- Development and Validation of a Risk Screening Model for Depressive Symptoms in Older Inpatients: A Cross-Sectional Study.Clinical interventions in aging · 2026Article
- The Role of Alexithymia in Social Learning and Feedback-Driven Social Inferences.Computational psychiatry (Cambridge, Mass.) · 2026Article
- Review
- Born to act: Deferred action and desire as active inference.Cognitive, affective & behavioral neuroscience · 2025Review
- The contribution of evidence-based practice and the practice-based evidence approaches to contemporary Australian psychology: implications for culturally safe practice.The Medical journal of Australia · 2025Article
- Perturbing whole-brain models of brain hierarchy: An application for depression following pharmacological treatment.Annals of the New York Academy of Sciences · 2025Article
- Electroencephalography Alpha Traveling Waves as Early Predictors of Treatment Response in Major Depressive Episodes: Insights from Intermittent Photic Stimulation.Biomedicines · 2025Article
- Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia.Neuroscience of consciousness · 2025Article
- Predictive coding in psychopathology: mechanistic model or metaphorical re-description?Frontiers in human neuroscience · 2025Review
- Is depression a global brain disorder with topographic dynamic reorganization?Translational psychiatry · 2024Review
- A new predictive coding model for a more comprehensive account of delusions.The lancet. Psychiatry · 2024Review
- I like therefore I can, and I can therefore I like: the role of self-efficacy and affect in active inference of allostasis.Frontiers in neural circuits · 2024Article
Corrections and comments
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3 authors.
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Abstract
Predictive coding models of brain processing propose that top-down cortical signals promote efficient neural signaling by carrying predictions about incoming sensory information. These "priors" serve to constrain bottom-up signal propagation where prediction errors are carried via feedforward mechanisms. Depression, traditionally viewed as a disorder characterized by negative cognitive biases, is associated with disrupted reward prediction error encoding and signaling. Accumulating evidence also suggests that depression is characterized by impaired local and long-range prediction signaling across multiple sensory domains. This review highlights the electrophysiological and neuroimaging evidence for disrupted predictive processing in depression. The discussion is framed around the manner in which disrupted generative predictions about the sensorium could lead to depressive symptomatology, including anhedonia and negative bias. In particular, the review focuses on studies of sensory deviance detection and reward processing, highlighting research evidence for both disrupted generative predictions and prediction error signaling in depression. The role of the monoaminergic and glutamatergic systems in predictive coding processes is also discussed. This review provides a novel framework for understanding depression using predictive coding principles and establishes a foundational roadmap for potential future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.