Evidence map›Paper›PMID 35308552›Full record

ArticleFrontiers in medicine2022

Mortality and Pulmonary Embolism in Acute Respiratory Distress Syndrome From COVID-19 vs. Non-COVID-19.

Demetrios J Kutsogiannis, Abdulrahman Alharthy, Abdullah Balhamar, Fahad Faqihi, John Papanikolaou, Saleh A Alqahtani, Ziad A Memish, Peter G Brindley, Laurent Brochard, Dimitrios Karakitsos

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Demetrios J KutsogiannisDepartment of Critical Care Medicine, Faculty of Medicine and Dentistry, The University of Alberta, Edmonton, AB, Canada.
Abdulrahman AlharthyCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Abdullah BalhamarCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Fahad FaqihiCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
John PapanikolaouCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Saleh A AlqahtaniDepartment of Medicine, The Johns Hopkins University Hospital, Baltimore, MD, United States.
Ziad A MemishResearch and Innovation Center, King Saud Medical City, Riyadh, Saudi Arabia.
Peter G BrindleyDepartment of Critical Care Medicine, Faculty of Medicine and Dentistry, The University of Alberta, Edmonton, AB, Canada.
Laurent BrochardDepartment of Critical Care, Keenan Research Center and Li Ka Shing Institute, St. Michael's Hospital, Toronto, ON, Canada.
Dimitrios KarakitsosCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
King Saud Medical City · SAUniversity of Alberta · CAJohns Hopkins Hospital · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: There may be a difference in respiratory mechanics, inflammatory markers, and pulmonary emboli in COVID-19 associated ARDS vs. ARDS from other etiologies. Our purpose was to determine differences in respiratory mechanics, inflammatory markers, and incidence of pulmonary embolism in patients with and without COVID-19 associated ARDS admitted in the same period and treated with a similar ventilation strategy. Methods: A cohort study of COVID-19 associated ARDS and non COVID-19 patients in a Saudi Arabian center between June 1 and 15, 2020. We measured respiratory mechanics (ventilatory ratio (VR), recruitability index (RI), markers of inflammation, and computed tomography pulmonary angiograms. Results: Forty-two patients with COVID-19 and 43 non-COVID patients with ARDS comprised the cohort. The incidence of "recruitable" patients using the recruitment/inflation ratio was slightly lower in COVID-19 patients (62 vs. 86%; Conclusion: COVID-19 patients were slightly less recruitable and had a higher incidence of pulmonary embolism than those with ARDS from other etiologies. A high D-dimer was predictive of pulmonary embolism in COVID-19 patients. COVID-19 infection was not an independent predictor of 60-day mortality in the presence of ARDS.

Indexed as

acute respiratory distress syndromeCOVID-19interleukin-6 (IL-6)pulmonary embolismrecruitment inflation ratiorespiratory mechanicsventilatory ratio

Identifiers

PMID35308552
PMCPMC8931188
OpenAlexW4214907091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.