Evidence map›Paper›PMID 35308551›Full record

ArticleFrontiers in medicine2022

Case Report: A Rare Case of Thrombotic Microangiopathy Induced by Remethylation Disorders.

Lu Pang, Jian Chen, Haiyan Yu, Haiming Huang, Bo Jin, Xin Wang, Haixia Li

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Prominent renal complications associated withFrontiers in pediatrics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lu PangDepartment of Clinical Laboratory, Peking University First Hospital, Beijing, China.
Jian ChenDepartment of Clinical Laboratory, Peking University First Hospital, Beijing, China.
Haiyan YuDepartment of Clinical Laboratory, Peking University First Hospital, Beijing, China.
Haiming HuangDepartment of Clinical Laboratory, Peking University First Hospital, Beijing, China.
Bo JinDepartment of Clinical Laboratory, Peking University First Hospital, Beijing, China.
Xin WangDepartment of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Haixia LiDepartment of Clinical Laboratory, Peking University First Hospital, Beijing, China.
Peking University · CNPeking University First Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this research, we described a very rare case of thrombotic microangiopathy induced by remethylation disorders. A 16-year-old boy presented to the emergency department with 5 months of weakness and fatigue. He was diagnosed with thrombotic microangiopathy based on clinical manifestation and laboratory information, which showed microangiopathic hemolytic anemia, renal impairment, and thrombocytopenia. After a complex diagnostic workup, the metabolite screening parameters and sequencing results guided us toward the diagnosis of remethylation disorders. The patient was diagnosed with thrombotic microangiopathy induced by remethylation disorders (cblC).

Indexed as

cblChemolytic uremic syndromeMMACHCremethylation disordersschistocytes

Identifiers

PMID35308551
PMCPMC8924285
OpenAlexW4214854857

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.