ArticlePhotoacoustics2022
Image processing improvements afford second-generation handheld optoacoustic imaging of breast cancer patients.
Article in Photoacoustics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Real-time quality control in optoacoustic mesoscopy for enhancing data quality and standardization in clinical studies.Photoacoustics · 2026Article
- Hybrid three-dimensional full-view multi-wavelength photoacoustic and ultrasound breast tomography.Photoacoustics · 2026Article
- Feasibility of the photoacoustic detection of haemophilia-related microbleeds: a preclinical study using isolated pig limbs.Thrombosis journal · 2026Article
- Motion score for spectral quality control of optoacoustic-ultrasound data.Scientific reports · 2026Article
- Low frequency detection in clinical multispectral optoacoustic tomography.Photoacoustics · 2025Article
- Fibrotic Disease: from Signaling Pathways and Biomarkers to Molecular Imaging.Molecular imaging and biology · 2025Review
- Advances in Photoacoustic Imaging of Breast Cancer.Sensors (Basel, Switzerland) · 2025Review
- Scale-equivariant deep model-based optoacoustic image reconstruction.Photoacoustics · 2025Article
- In vivo photoacoustic tomography of porcine abdominal organs using Fabry-Pérot sensing integrated platform.European radiology experimental · 2025Article
- Exploring the Evolution of Breast Cancer Imaging: A Review of Conventional and Emerging Modalities.Cureus · 2025Review
- A primer on current status and future opportunities of clinical optoacoustic imaging.Npj imaging · 2025Review
- Bayesian modeling with locally adaptive prior parameters in small animal imaging.Frontiers in nuclear medicine · 2025Article
- Mini review of photoacoustic clinical imaging: a noninvasive tool for disease diagnosis and treatment evaluation.Journal of biomedical optics · 2024Review
- A novel maternal thyroid disease prediction using multi-scale vision transformer architecture with improved linguistic hedges neural-fuzzy classifier.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Mixture prior distributions and Bayesian models for robust radionuclide image processing.Frontiers in nuclear medicine · 2024Article
- Advances in photoacoustic imaging aided by nano contrast agents: special focus on role of lymphatic system imaging for cancer theranostics.Journal of nanobiotechnology · 2023Review
- Spotlight on Nerves: Portable Multispectral Optoacoustic Imaging of Peripheral Nerve Vascularization and Morphology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Adaptive dual-speed ultrasound and photoacoustic computed tomography.Photoacoustics · 2022Article
- Multispectral optoacoustic tomography forPhotoacoustics · 2022Article
- Optical Breast Imaging: A Review of Physical Principles, Technologies, and Clinical Applications.Journal of breast imagingArticle
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Since the initial breast transillumination almost a century ago, breast cancer imaging using light has been considered in different implementations aiming to improve diagnostics, minimize the number of available biopsies, or monitor treatment. However, due to strong photon scattering, conventional optical imaging yields low resolution images, challenging quantification and interpretation. Optoacoustic imaging addresses the scattering limitation and yields high-resolution visualization of optical contrast, offering great potential value for breast cancer imaging. Nevertheless, the image quality of experimental systems remains limited due to a number of factors, including signal attenuation with depth and partial view angle and motion effects, particularly in multi-wavelength measurements. Methods: We developed data analytics methods to improve the accuracy of handheld optoacoustic breast cancer imaging, yielding second-generation optoacoustic imaging performance operating in tandem with ultrasonography. Results: We produced the most advanced images yet with handheld optoacoustic examinations of the human breast and breast cancer, in terms of resolution and contrast. Using these advances, we examined optoacoustic markers of malignancy, including vasculature abnormalities, hypoxia, and inflammation, on images obtained from breast cancer patients. Conclusions: We achieved a new level of quality for optoacoustic images from a handheld examination of the human breast, advancing the diagnostic and theranostic potential of the hybrid optoacoustic-ultrasound (OPUS) examination over routine ultrasonography.
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