Evidence map›Paper›PMID 35308080›Full record

ArticleJournal of carbohydrate chemistry2021

Synthetic linear glycopolymers and their biological applications.

Qian Qin, Shuyao Lang, Xuefei Huang

Abstract read
In one paragraph

Article in Journal of carbohydrate chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qian QinDepartment of Chemistry, Michigan StateUniversity, East Lansing, MI, USA.
Shuyao LangDepartment of Chemistry, Michigan StateUniversity, East Lansing, MI, USA.
Xuefei HuangDepartment of Chemistry, Michigan StateUniversity, East Lansing, MI, USA.ORCID 0000-0002-6468-5526

Funding

Generation of active immunity against cytotoxic oligomeric tau speciesR01CA225105 · NCI · MICHIGAN STATE UNIVERSITY · PI HUANG, XUEFEI · 2018 to 2023
$2.8M
Synthetic glycan conjugates with bacteriophage Qbeta for broad spectrum anti-salmonella vaccinesR01AI146210 · NIAID · MICHIGAN STATE UNIVERSITY · PI HUANG, XUEFEI · 2019 to 2023
$1.5M
NCI NIH HHS R01 CA225105NIAID NIH HHS R01 AI146210
6 · The paper itself

Abstract

As typical affinities of carbohydrates with their receptors are modest, polymers of carbohydrates (glycopolymers) are exciting tools to probe the multifaceted biological activities of glycans. In this review, the linear glycopolymers and the multivalency effects are first introduced. This is followed by discussions of methods to synthesize these polymers. Subsequently, the interactions of glycopolymers with plant lectins and viral/bacterial carbohydrate binding proteins are discussed. In addition, applications of the glycopolymers in facilitating glycan microarray studies, mimicking cell surface glycans, modulation of the immune system, cryoprotection of protein, and electron-beam lithography are presented to stimulate further development of this fascinating technology.

Indexed as

Biological applicationsglycopolymerssynthesis

Identifiers

PMID35308080
PMCPMC8932951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.