ArticleOsteoarthritis and cartilage2022
Association between hamstring coactivation during isokinetic quadriceps strength testing and knee cartilage worsening over 24 months.
Article in Osteoarthritis and cartilage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Associations of muscle coactivation patterns with gait, muscle strength, and symptoms across different stages of knee osteoarthritis.Knee surgery & related research · 2026Article
- Kinesio taping in knee osteoarthritis: mechanisms, clinical evidence, and rehabilitation implementations.Rheumatology international · 2026Review
- Knee muscle strength as a mediator of sex differences in incident knee osteoarthritis.Arthritis research & therapy · 2026Article
- Electromyographic analysis of muscle activation and co-activation across smash phases in para-badminton: an exploratory investigation of neuromuscular coordination.Frontiers in bioengineering and biotechnology · 2026Article
- Functional deficits after anterior cruciate ligament injury are associated with altered neuromuscular control: a cross-sectional study.Frontiers in medicine · 2026Article
- Strain mapping using compressed sensing accelerated 4D flow MRI-Potential for detecting coactivation in thigh muscles.Frontiers in physiology · 2025Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveThis study aimed to determine longitudinal associations, including sex-specific differences, between greater knee flexor antagonist coactivation and worsening cartilage morphology in knees with or at risk for osteoarthritis (OA).
designBaseline measurements were collected at the 60-month visit of a longitudinal osteoarthritis study following community-dwelling participants (MOST). Knee flexor and extensor muscle activity were measured with surface electromyography during a maximal isokinetic knee extension task. MRI analyzed knee cartilage morphology at baseline and 24-month follow-up. Multivariable adjusted logistic regression models were used to assess associations between coactivation level and cartilage morphology worsening.
resultsAnalysis of 373 women (mean ± SD age 67.4 ± 7.3 years and BMI 29.7 ± 5.0 kg/m
conclusionsThese findings suggest a longitudinal relationship between antagonist hamstring coactivation during isokinetic knee extensor testing and worsening of cartilage morphology over 24 months in men with or at risk for knee OA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.