ArticleEnvironmental science & technology2022
Time to Break the "Lock-In" Impediments to Chemicals Management.
Article in Environmental science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Deciphering the Chemical Footprint of Renewables.Environmental science & technology · 2026Article
- Planetary Boundary for Novel Entities: Time for a Reboot.Environmental science & technology · 2026Review
- The Role of ES&T in Advancing Environmental Toxicology and Chemical Risk Assessment: Past, Present, and Future.Environmental science & technology · 2026Review
- Breaking Lock-ins to Enable a Green Pharmacy.Environmental science & technology · 2026Review
- Boundaries, Limits, Global Threats - How Can the Impacts of Global Synthetic Pollutants Be Reduced?Environmental science & technology · 2026Review
- A Hazard-Based Approach Enables the Efficient Identification of Chemicals of Concern in Plastics.Environmental science & technology · 2025Review
- From Ambition to Action: Navigating Obstacles and Opportunities of "Safe and Sustainable by Design".Environmental science & technology · 2025Review
- Conflicts of Interest in the Assessment of Chemicals, Waste, and Pollution.Environmental science & technology · 2023Review
- Integrated data-driven cross-disciplinary framework to prevent chemical water pollution.One earth (Cambridge, Mass.) · 2023Article
- Optimizing Chemicals Management in the United States and Canada through the Essential-Use Approach.Environmental science & technology · 2023Review
- A science-based agenda for health-protective chemical assessments and decisions: overview and consensus statement.Environmental health : a global access science source · 2023Article
- Integrating a Chemicals Perspective into the Global Plastic Treaty.Environmental science & technology letters · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite enormous national, regional, and global efforts on chemical management, the widespread use of hazardous chemicals continues in many parts of the world even after decades of there being well-known risks to public and/or ecosystem health. This continued supply and use, despite strong evidence of negative impacts, is not unique to chemicals management. In the field of climate change, the concept of "lock-in" has been used to explain the complex interactions among economic, social, technological, and political dynamics that reinforce global reliance on the extraction and use of fossil fuels. Learning from carbon "lock-in" phenomena, this Perspective explores the challenges of chemicals management from the perspective of lock-in through three case studies: paraquat, perfluorooctanesulfonic acid (PFOS), and asbestos. These case studies illustrate that most current chemicals management frameworks fail to address the concerns arising from this complex interplay by not involving all relevant stakeholder groups that are part of lock-in, from producers to consumers. This results in a relatively narrow consideration (e.g., only demand but not supply) of the effectiveness and consequences of regulations. We submit that to break lock-in and address the global threat of chemical pollution, current approaches to managing hazardous chemicals should be broadened to take a comprehensive approach to understanding and managing factors contributing to lock-in, notably both supply and demand on national and international scales.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.