Evidence map›Paper›PMID 35306694›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2022

Peroxiredoxin-2 recycling is slower in denser and pediatric sickle cell red cells.

Joo-Yeun Oh, Chae Yun Bae, Malgorzata Kasztan, David M Pollock, Robert T Russell, Jeffrey Lebensburger, Rakesh P Patel

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Ferroptosis as an emerging target in sickle cell disease.Current research in toxicology · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joo-Yeun OhDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Chae Yun BaeDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Malgorzata KasztanPediatric Hematology Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
David M PollockSection of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Robert T RussellDivision of Pediatric Surgery, Department of Surgery, Children's of Alabama, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jeffrey LebensburgerPediatric Hematology Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Rakesh P PatelDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-1526-4303
University of Alabama at Birmingham · USChildren's of Alabama · US

Funding

The Role of Endothelin-1 in Tubular Injury in Sickle Cell DiseaseR00HL144817 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KASZTAN, MALGORZATA · 2021 to 2023
$747k
Acute Kidney Injury During Sickle Cell CrisisR03HL144485 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEBENSBURGER, JEFFREY D · 2018 to 2019
$149k
NHLBI NIH HHS R00 HL144817NHLBI NIH HHS R03 HL144485
6 · The paper itself

Abstract

Peroxiredoxin-2 (Prx-2) is a critical antioxidant protein in red blood cells (RBC). Prx-2 is oxidized to a disulfide covalently-bound dimer by H

Indexed as

Anemia, Sickle CellPeroxiredoxinsAgedAnimalsAntioxidantsErythrocytesHumansMicePeroxidaseAntioxidantsPeroxidasePeroxiredoxinsantioxidanthemoglobinhydrogen peroxideRed blood cellssickle cell disease

Identifiers

PMID35306694
PMCPMC10155932
OpenAlexW4220804860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.