Evidence map›Paper›PMID 35306659›Full record

ArticleEuropean journal of clinical investigation2022

Re-infection in COVID-19: Do we exaggerate our worries?

Yusuf Arslan, Fethiye Akgul, Bunyamin Sevim, Zeynep Sedef Varol, Suda Tekin

Open access · greenAbstract read
In one paragraph

Article in European journal of clinical investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Safety and efficiency of COVID-19 vaccine in North Africa.Human vaccines & immunotherapeutics · 2024
    Article
  5. Article
  6. Article
  7. Re-infection in COVID-19: Do we exaggerate our worries?European journal of clinical investigation · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Yusuf ArslanDepartment of Infectious Diseases and Clinical Microbiology, Batman Training and Research Hospital, Batman, Turkey.ORCID https://orcid.org/0000-0002-1479-6009
Fethiye AkgulDepartment of Infectious Diseases and Clinical Microbiology, Batman Training and Research Hospital, Batman, Turkey.
Bunyamin SevimBatman Provincial Health Directorate, TR Ministry of Health, Batman, Turkey.
Zeynep Sedef VarolPublic Health Department, Division of Epidemiology, School of Medicine, Dokuz Eylül University, Izmir, Turkey.
Suda TekinDepartment of Infectious Diseases and Clinical Microbiology, School of Medicine, Koç University, Istanbul, Turkey.
Batman University · TRDokuz Eylül University · TRKoç University · TRMinistry of Health · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProtective long-term immunity following coronavirus disease 2019 (COVID-19) is unclear. The study evaluated the relationship between the vaccination status and risk factors in the re-infection of patients with a diagnosis of COVID-19 who reported to the Public Health Management System in a province in south-eastern Turkey.

methodsPatients with positive results for the severe acute respiratory syndrome coronavirus 2 by the real-time reverse transcription polymerase chain reaction (RT-PCR) test in respiratory samples were defined as confirmed cases. Reinfection was diagnosed in cases with COVID-19 real-time RT-PCR positivity, with or without COVID-19-like symptoms, in at least 90 days after the first infection/disease.

resultsA total of 58 811 patients with the diagnosis of COVID-19 from March 11, 2020, to August 31, 2021, were included in the study. Re-infection was detected in 421 (0.7%) of all patients. The mean age of the cases was 38.0±16.0 years, and 51% of them were female. Eight (2.0%) of the cases resulted in death due to re-infection. No hospitalization or mortality was observed in fully vaccinated patients. Additionally, none of the mortal cases had completed the vaccination schedule.

conclusionsWe are concerned that the re-infection rates and mortality may increase due to new variant strains. Vaccination is the greatest weapon against progression to critical illness in re-infections, even with existing mutations. Therefore, it is important for those without a full vaccination schedule to be vaccinated, even if they have been previously infected.

Indexed as

COVID-19AdultFemaleHospitalizationHumansMaleMiddle AgedReinfectionSARS-CoV-2VaccinationYoung AdultcoronavirusCOVID-19re-infectionSARS-CoV-2vaccination

Identifiers

PMID35306659
PMCPMC9111805
OpenAlexW4220820352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.