Evidence map›Paper›PMID 35306606›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Effect of physical activity on fatigue in childhood cancer survivors: a systematic review.

Libby Moberg, Jordan Fritch, Danielle Westmark, Daniel Santa Mina, Crystal Krause, Laura Bilek, Melissa Acquazzino

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Metabolic Implications of Childhood Cancer.Current pediatrics reports · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Libby MobergDepartment of Surgery, University of Nebraska Medical Center, Omaha, NE, USA.
Jordan FritchDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA.
Danielle WestmarkLeon S. McGoogan Health Sciences Library, University of Nebraska Medical Center, Omaha, NE, USA.
Daniel Santa MinaDepartment of Kinesiology and Physical Education, University of Toronto, Toronto, Canada.
Crystal KrauseDepartment of Surgery, University of Nebraska Medical Center, Omaha, NE, USA.
Laura BilekCollege of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE, USA.
Melissa AcquazzinoDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA. macquazzino@childrensomaha.org.ORCID http://orcid.org/0000-0001-6736-0308
University of Nebraska Medical Center · USChildren's Hospital & Medical Center · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMany children, adolescents, and young adult survivors of childhood cancer experience fatigue following cancer treatment. Physical activity has been shown to be effective in improving cancer-related fatigue in adult survivors, but there is a lack of evidence on its effect in childhood cancer survivors. In addition, there are no guidelines for treatment of fatigue in childhood cancer survivors. The purpose of this study was to examine the existing literature on the effect of physical activity on fatigue in children, adolescents, and young adult survivors of childhood cancer.

methodsWe conducted a systematic review to examine the effect of physical activity on fatigue in children, adolescents, and young adult survivors of childhood cancer.

resultsNine studies were included. Most of the studies included reported an increase in physical activity and a decline in fatigue in the target patient population. Interpretation of these findings is limited due to small sample sizes, inadequate length of follow-up, and variability among reviewed studies. Quantitative analysis was not conducted due to significant variability in both the type of physical activity implemented and in the measurement of fatigue.

conclusionsFurther research, with a larger sample size and consistency in both physical activity interventions and measurement of fatigue, is needed to add greater precision and confidence in the effect of physical activity on fatigue in childhood cancer survivors. Results of this research will help guide future recommendations on physical activity for the treatment of cancer-related fatigue in children, adolescents, and young adult survivors of childhood cancer.

Indexed as

Cancer SurvivorsNeoplasmsAdolescentChildExerciseFatigueHumansQuality of LifeYoung AdultFatiguePediatric cancerPhysical activitySurvivorship

Identifiers

PMID35306606
OpenAlexW4221097594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.