ArticleJapanese journal of ophthalmology2022
Association between peripheral visual field defects and focal lamina cribrosa defects in highly myopic eyes.
Article in Japanese journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Interaction of Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Pathophysiology and Clinical Implications.Journal of clinical medicine · 2026Review
- Characteristics of visual field in myopic patients using Easyfield perimeter and its application in preoperative glaucoma screening of corneal refractive surgery.International ophthalmology · 2025Article
- Outcomes of standalone ab interno trabeculotomy in the treatment of open-angle glaucoma in eyes with high myopia.BMC ophthalmology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeWe aimed to identify peripheral visual field (VF) defect pathogenesis in high myopia using optical coherence tomography (OCT) and microperimetry and to investigate the association between focal lamina cribrosa defects (fLCDs) and high myopia-specific peripheral visual field defects (HM-pVFDs). STUDY
designRetrospective case-control study.
methodsThirty-five highly myopic patients (refractive error ≥ 8.0 D or axial length > 26.5 mm) with an HM-pVFD, diagnosed using the V-4 isopter in Goldmann perimetry, and 35 age- and 35 sex-matched controls were studied. The optic nerve head (ONH) morphology was analyzed by use of OCT; retinal light sensitivities around the ONH were evaluated by use of microperimetry. The main outcome measures were best-corrected visual acuity (BCVA), axial length (AL), refractive error, intraocular pressure (IOP), the OCT findings, and the microperimetry findings.
resultsThe BCVA, AL, IOP, and refractive error did not differ significantly between the patient and the control groups. Of the 35 eyes with an HM-pVFD, twenty-four had fLCDs detected by use of OCT, one showed no evidence of fLCDs, and ten had inadequate images due to excessive ONH tilting. Of the 35 control eyes, two had fLCDs, twenty-eight showed no evidence of fLCDs, and five had inadequate images. The peripapillary retinal light sensitivity was decreased in 29 of the 35 eyes with an HM-pVFD; no such decrease was noted in 30 of the 35 control eyes. Peripheral VF abnormality detection by use of microperimetry had 82.9% sensitivity and 85.7% specificity.
conclusionsOur findings indicate an important relationship between HM-pVFDs and fLCDs, suggesting fLCD involvement in peripheral VF abnormality pathogenesis in highly myopic patients. Furthermore, microperimetry is reproducible for evaluating HM-pVFDs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.