Evidence map›Paper›PMID 35306541›Full record

ArticleProstate cancer and prostatic diseases2023

Localized prostate cancer disparities in risk group at presentation and access to treatment for Hispanic men.

Nishwant Swami, Yefri A Baez, Idalid Franco, Tiffany Nguyen, Karthik Meiyappan, Minh Ton, Bhav Jain, Crystal Seldon, Kenrick Ng, Narjust Duma and 5 more

Abstract read
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In one paragraph

Article in Prostate cancer and prostatic diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  6. Geographic variability in contemporary utilization of PET imaging for prostate cancer: a medicare claims cohort study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
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  9. Review
  10. Prostate Cancer Disparities in Clinical Characteristics and Survival among Black and Latino Patients Considering Nativity: Findings from the California Cancer Registry.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Nishwant SwamiUniversity of Massachusetts Medical School, Worcester, MA, USA.ORCID 0000-0002-3825-8678
Yefri A BaezDepartment of Urology, Brigham and Women's Hospital, Boston, MA, USA.
Idalid FrancoHarvard Medical School, Boston, MA, USA.
Tiffany NguyenUniversity of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center, Miami, Fl, USA.
Karthik MeiyappanUniversity of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center, Miami, Fl, USA.
Minh TonUniversity of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center, Miami, Fl, USA.
Bhav JainMassachusetts Institute of Technology, Cambridge, MA, UK.ORCID 0000-0003-2648-4894
Crystal SeldonDepartment of Radiation Oncology, University of Miami/Jackson Memorial Hospital, Miami, USA.
Kenrick NgDepartment of Medical Oncology, Mount Vernon Cancer Centre, Northwood, UK.ORCID 0000-0001-9132-4075
Narjust DumaDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Mohammed AlshalalfaUniversity of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center, Miami, Fl, USA.ORCID 0000-0001-8405-3035
Kosj YamoahDepartment of Radiation Oncology, H. Lee Moffitt Cancer Center & Research Institute, University of South Florida, Tampa, Fl, USA.ORCID 0000-0001-9055-3538
Paul L NguyenHarvard Medical School, Boston, MA, USA.
Brandon A MahalDepartment of Radiation Oncology, University of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center, Miami, Fl, USA. bmahal@med.miami.edu.ORCID 0000-0001-5406-3232
Edward Christopher DeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. deee1@mskcc.org.ORCID 0000-0001-6119-0889
University of Miami · USBrigham and Women's Hospital · USHarvard University · USMassachusetts Institute of Technology · USMemorial Sloan Kettering Cancer Center · USMount Vernon Cancer Centre · GBUniversity of South Florida · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Biomarker Approaches to Individualizing Systemic Therapy for High Risk Prostate CancerR01CA240582 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FENG, FELIX YI-CHUNG, NGUYEN, PAUL L · 2020 to 2024
$3.4M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA240582
6 · The paper itself

Abstract

backgroundDespite great heterogeneity amongst Hispanic groups, prostate cancer studies often report Hispanic patients in aggregate. We sought to identify differences in prostate cancer risk group at presentation and treatment status among Hispanic subgroup populations.

methodsPatients with localized prostate adenocarcinoma diagnosed from 2004-2017 were identified in the National Cancer Database (NCDB) and disaggregated by racial subgroup and Hispanic country of origin. Ordinal logistic regression defined adjusted odds ratios (AORs) with 95% CI of (1) presenting at progressively higher risk group and (2) receiving treatment with intermediate-unfavorable or high-risk disease.

resultsIn our sample (n = 895,087), Hispanic men had greater odds of presenting with higher-risk localized prostate cancer compared with non-Hispanic White men (AOR = 1.18 95% CI 1.16-1.21, p < 0.001). Additionally, Hispanic Black men were less likely to present with higher-risk disease than non-Hispanic Black men. Disparities also existed when disaggregated by country of origin, particularly for Mexican men. Amongst men with unfavorable-risk disease, Hispanic men were less likely to receive treatment than non-Hispanic White men (95% CI 0.57-0.67, p < 0.001). The odds of Hispanic Black patients receiving treatment was 2.00 times the odds (95% CI 1.17-3.41 p = 0.011) of non-Hispanic Black patients receiving treatment. Upon disaggregation by country of origin, disparities persisted, particularly for Mexican men.

conclusionWe found marked heterogeneity when risk group at presentation and treatment for higher-risk disease were disaggregated by racial subgroup and country of origin. Our findings support further collection of disaggregated data in Hispanic communities and study of potential mechanisms underlying the observed differences.

Indexed as

Healthcare DisparitiesHispanic or LatinoProstatic NeoplasmsBlack or African AmericanHealth Services AccessibilityHumansMale

Identifiers

PMID35306541
OpenAlexW4221068650

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.