ArticleScientific reports2022
Synthesis of new series of quinoline derivatives with insecticidal effects on larval vectors of malaria and dengue diseases.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 46 citations in OpenAlex.
- Exploring insecticidal activity and SAR study of newly synthesized Benzo[h]quinoline-based heterocycles against Aphis craccivora Koch. and Culex pipiens L. Larvae.Scientific reports · 2026Article
- In vitro larvicidal activity of selected azabenzimidazole and diarylquinoline derivatives against Anopheles gambiae and in silico mechanistic analysis.Molecular diversity · 2026Article
- Ultrasound-mediated Tandem Synthesis of New Highly Functionalized 4-Hydroxy-quinoline Derivatives with Amidine and Imidate Skeletons from Trichloroacet-amidine(imidate), Alkynes, and Isatoic Anhydride.Current organic synthesis · 2026Article
- Antiviral agents for dengue virus.Virologica Sinica · 2025Review
- Effects of 4‑Alkoxy/Amino-7-Chloroquinolines onACS omega · 2025Article
- Quinoline: A Novel Solution for Next-Generation Pesticides, Herbicides, and Fertilizers.Applied biochemistry and biotechnology · 2025Review
- Synthetic Strategies for the Development of Novel Heterocycles as Larvicides TargetingMedicinal chemistry (Shariqah (United Arab Emirates)) · 2025Review
- Exploring Quinoline Derivatives: Their Antimalarial Efficacy and Structural Features.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025Review
- Screening of the antileishmanial and antiplasmodial potential of synthetic 2-arylquinoline analogs.Scientific reports · 2023Article
- Crystal structure and Hirshfeld surface analysis of 8-aza-niumylquinolinium tetra-chlorido-zincate(II).Acta crystallographica. Section E, Crystallographic communications · 2023Article
- Antiplasmodial Properties of Aqueous and Ethanolic Extracts of Ten Herbal Traditional Recipes Used in Thailand againstTropical medicine and infectious disease · 2022Article
- Recent advances in chemistry and therapeutic potential of functionalized quinoline motifs - a review.RSC advances · 2022Review
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Authors and funding
18 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquito borne diseases are on the rise because of their fast spread worldwide and the lack of effective treatments. Here we are focusing on the development of a novel anti-malarial and virucidal agent with biocidal effects also on its vectors. We have synthesized a new quinoline (4,7-dichloroquinoline) derivative which showed significant larvicidal and pupicidal properties against a malarial and a dengue vector and a lethal toxicity ranging from 4.408 µM/mL (first instar larvae) to 7.958 µM/mL (pupal populations) for Anopheles stephensi and 5.016 µM/mL (larva 1) to 10.669 µM/mL (pupae) for Aedes aegypti. In-vitro antiplasmodial efficacy of 4,7-dichloroquinoline revealed a significant growth inhibition of both sensitive strains of Plasmodium falciparum with IC
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