Evidence map›Paper›PMID 35306171›Full record

ArticleClinical immunology (Orlando, Fla.)2022

Equine immunoglobulin fragment F(ab')

Divya Gupta, Farhan Ahmed, Dixit Tandel, Haripriya Parthasarathy, Dhiviya Vedagiri, Vishal Sah, B Krishna Mohan, Rafiq Ahmad Khan, Chiranjeevi Kondiparthi, Prabhudas Savari and 5 more

Open access · greenAbstract read
In one paragraph

Article in Clinical immunology (Orlando, Fla.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Hyperimmune Globulins in COVID-19.Current topics in microbiology and immunology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Divya GuptaCentre for Cellular and Molecular Biology, Hyderabad 500007, Telangana, India.
Farhan AhmedSchool of Life Sciences, Department of Animal Biology, University of Hyderabad, Hyderabad 500046, Telangana, India.
Dixit TandelCentre for Cellular and Molecular Biology, Hyderabad 500007, Telangana, India; Academy for Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Haripriya ParthasarathyCentre for Cellular and Molecular Biology, Hyderabad 500007, Telangana, India.
Dhiviya VedagiriCentre for Cellular and Molecular Biology, Hyderabad 500007, Telangana, India; Academy for Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Vishal SahCentre for Cellular and Molecular Biology, Hyderabad 500007, Telangana, India; Academy for Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
B Krishna MohanVINS Bio Products Limited, Hyderabad 500034, Telangana, India.
Rafiq Ahmad KhanSchool of Life Sciences, Department of Animal Biology, University of Hyderabad, Hyderabad 500046, Telangana, India.
Chiranjeevi KondiparthiVINS Bio Products Limited, Hyderabad 500034, Telangana, India.
Prabhudas SavariVINS Bio Products Limited, Hyderabad 500034, Telangana, India.
Sandesh JainVINS Bio Products Limited, Hyderabad 500034, Telangana, India.
Shashikala ReddyDepartment of Microbiology, Osmania Medical College, Koti, Hyderabad 500096, Telangana, India.
Jerald Mahesh KumarCentre for Cellular and Molecular Biology, Hyderabad 500007, Telangana, India.
Nooruddin KhanSchool of Life Sciences, Department of Animal Biology, University of Hyderabad, Hyderabad 500046, Telangana, India.
Krishnan Harinivas HarshanCentre for Cellular and Molecular Biology, Hyderabad 500007, Telangana, India; Academy for Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: hkrishnan@ccmb.res.in.
Biological E (India) · INCentre for Cellular and Molecular Biology · INUniversity of Hyderabad · INOsmania Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutralizing antibody-based passive immunotherapy could be an important therapeutic option against COVID-19. Herein, we demonstrate that equines hyper-immunized with chemically inactivated SARS-CoV-2 elicited high antibody titers with a strong virus-neutralizing potential, and F(ab')

Indexed as

COVID-19SARS-CoV-2AnimalsAntibodies, NeutralizingAntibodies, ViralHorsesHumansImmunoglobulin Fab FragmentsImmunoglobulin FragmentsRabbitsAntibodies, NeutralizingAntibodies, ViralImmunoglobulin Fab FragmentsImmunoglobulin FragmentsAntiseraCOVID-19F(ab’)(2)Passive immunotherapySARS-CoV-2Virus neutralization

Identifiers

PMID35306171
PMCPMC8926440
OpenAlexW4221133230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.