Evidence map›Paper›PMID 35305995›Full record

Trial reportPreventive medicine2022

A multilevel, low literacy dual language intervention to promote colorectal cancer screening in community clinics in Florida: A randomized controlled trial.

Shannon M Christy, Steven K Sutton, Rania Abdulla, Carol Boxtha, Paola Gonzalez, Lakeshia Cousin, Aldenise Ewing, Samantha Montoya, Diana Lopez, Tina Beehler and 4 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03906110 (Community Colorectal Cancer Awareness, Research, Education & Screening), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03906110 completednot on this map

Community Colorectal Cancer Awareness, Research, Education & Screening (C-CARES) : A Multilevel Intervention to Increase Colorectal Cancer Screening Adherence In Community Clinics

TypeobservationalSponsorH. Lee Moffitt Cancer Center and Research InstituteRan2018 to 2022Enrolled327ConditionsColorectal CancerArmsCommunity Colorectal Cancer Awareness, Research, Education & Screening (C-CARES) Materials, Contact Message, Personalized One on One Education, Fecal Immunochemical Test (FIT)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Shannon M ChristyH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America; Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America. Electronic address: shannon.christy@moffitt.org.
Steven K SuttonH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America; Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.
Rania AbdullaH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Carol BoxthaH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Paola GonzalezFormerly with H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Lakeshia CousinFormerly with H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America; University of Florida, Gainesville, Florida, United States of America.
Aldenise EwingFormerly with H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America; Ohio State University, Columbus, Ohio, United States of America.
Samantha MontoyaH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Diana LopezSuncoast Community Health Centers, Inc., Brandon, Florida, United States of America.
Tina BeehlerPremier Community HealthCare Group, Inc., Dade City, Florida, United States of America.
Julian SanchezH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America; Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.
Rodrigo CarvajalH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Cathy D MeadeH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America; Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.
Clement K GwedeH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America; Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.
Moffitt Cancer Center · USUniversity of South Florida · USPremier Community Health · USSuncoast Hospice Institute · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Daniel G. Stover · 1985 to 2026
$132.3M
TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Together: Transforming and Translating Discovery to Improve HealthKL2TR001429 · NCATS · UNIVERSITY OF FLORIDA · PI GUIRGIS, FAHEEM W, LEEUWENBURGH, CHRISTIAAN · 2015 to 2023
$5.5M
Behavioral Oncology Education & Career DevelopmentR25CA090314 · NCI · H. LEE MOFFITT CANCER CTR &RES INST · PI BRANDON, THOMAS H · 2003 to 2018
$4.0M
Behavioral Oncology Education & Career DevelopmentT32CA090314 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI Vani N Simmons, SUSAN T VADAPARAMPIL · 2019 to 2026
$2.9M
NCATS NIH HHS KL2 TR001429NCI NIH HHS P30 CA016058NCI NIH HHS P30 CA076292NCI NIH HHS R25 CA090314NCI NIH HHS T32 CA090314
6 · The paper itself

Abstract

One of the largest disparities in cancer mortality in the United States occurs with colorectal cancer (CRC). The objectives of this multilevel two-arm intervention trial were to compare the efficacy of two interventions to promote CRC screening (CRCS) with fecal immunochemical test (FIT) and examine sociodemographic and psychosocial predictors of FIT screening. Individuals ages 50-75 (n = 326) who were not up-to-date with CRCS, could understand English or Spanish, and were at average CRC risk were recruited from two federally qualified health centers (FQHCs) in Florida. Prior to intervention, CRCS rates in the FQHCs were 27.1% and 32.9%, respectively. Study enrollment occurred April 2018-November 2019. System-level intervention components included leveraging electronic medical record (EMR) systems and delivering patient reminders. Participants were randomized to C-CARES (education+FIT) or C-CARES Plus (C-CARES+personalized coaching [for those not completing FIT within 90 days]). Primary outcome was completed FIT returned <1 year. Primary outcome analyses were performed using logistic regression. 225 participants completed FIT (69.0% [95% CI: 64.0-74.0%]), with no significant difference in FIT uptake by intervention arm (67.3% C-CARES Plus vs. 70.8% C-CARES; p = .49). FIT uptake was significantly higher among patients who received intervention materials in Spanish (77.2%) compared to those who received materials in English (63.2%, p < .01). The personalized coaching in the C-CARES Plus arm did not appear to provide added benefit beyond the C-CARES intervention. Multilevel approaches that include EMR prompts, reminders, FIT access, and provision of low-literacy, language-concordant education can support efforts to improved community clinics' CRCS rates. Future efforts should focus on repeat FIT screening. Trial registration: The trial was registered at ClinicalTrials.gov (NCT03906110).

Indexed as

Colorectal NeoplasmsLiteracyAgedEarly Detection of CancerFloridaHumansMass ScreeningMiddle AgedOccult BloodUnited StatesColorectal cancer screeningFecal immunochemical testFederally qualified health centerLow literacy English and Spanish language patient educationMultilevel interventionRandomized controlled trial

Identifiers

PMID35305995
PMCPMC9018599
OpenAlexW4220662845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.