Evidence map›Paper›PMID 35305851›Full record

Observational studyAnnals of emergency medicine2022

Subsequent Buprenorphine Treatment Following Emergency Physician Buprenorphine Prescription Fills: A National Assessment 2019 to 2020.

Bradley D Stein, Brendan Saloner, Rose Kerber, Mark Sorbero, Adam J Gordon

Abstract readObservational Study
In one paragraph

Observational study in Annals of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bradley D SteinRAND Corporation, Pittsburgh, PA. Electronic address: stein@rand.org.
Brendan SalonerDepartment of Health Policy and Management, Johns Hopkins University, Baltimore MD.
Rose KerberBoston, MA.
Mark SorberoRAND Corporation, Pittsburgh, PA.
Adam J GordonProgram for Addiction Research, Knowledge, and Advocacy, University of Utah School of Medicine, and VA Salt Lake City Health Care System, Salt Lake City, UT.

Funding

Optimal Methods for Estimating Policy Effect Heterogeneity in Opioid Policy ResearchP50DA046351 · NIDA · RAND CORPORATION · PI Rosalie Liccardo Pacula · 2018 to 2026
$20.8M
Quality of Medication Treatment for Opioid Use Disorder in Medicaid-enrollees: The Effects of State Policies and IntiativesR01DA045800 · NIDA · RAND CORPORATION · PI STEIN, BRADLEY D · 2018 to 2022
$2.9M
Improving Access and Quality of care for Medicaid-Eligible Adults with Opioid Use DisorderK01DA042139 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SALONER, BRENDAN K · 2017 to 2021
$917k
NIDA NIH HHS K01 DA042139NIDA NIH HHS P50 DA046351NIDA NIH HHS R01 DA045800
6 · The paper itself

Abstract

STUDY

objectiveBuprenorphine treatment for opioid use disorder provided in the emergency department with subsequent buprenorphine treatment by community prescribers is associated with improved outcomes, but the frequency with which this occurs is unknown. We examined the rates of subsequent buprenorphine treatment for buprenorphine-naïve individuals filling buprenorphine prescriptions from emergency physicians and initiated buprenorphine treatment and how such rates varied before and during the coronavirus disease 2019 (COVID-19) pandemic.

methodsUsing pharmacy claims capturing an estimated 92% of prescriptions filled at US retail pharmacies, we identified buprenorphine prescriptions filled between February 1, 2019, and November 30, 2020, written by emergency physicians. In this observational study, we calculated the rate at which patients subsequently filled buprenorphine prescriptions from other nonemergency clinicians, the frequency with which subsequent filled prescriptions were from different types of prescribers, and the changes in the rates of subsequent prescriptions following the declaration of the COVID-19 public health emergency.

resultsWe identified 22,846 prescriptions written by emergency physicians and filled by buprenorphine-naïve patients. They were most commonly paid for by Medicaid and were in metropolitan counties; 28.5% of patients subsequently filled buprenorphine prescriptions written by other clinicians. Adult primary care physicians and advanced practice providers (eg, physician assistants and nurse practitioners) were responsible for most of the subsequent prescriptions. The rates of subsequent prescriptions were 3.5% lower after the COVID-19 public health emergency declaration.

conclusionThe majority of patients filling buprenorphine prescriptions written by emergency physicians do not subsequently fill prescriptions written by other clinicians, and the rates of subsequent prescriptions were lower after the declaration of the COVID-19 public health emergency. These findings highlight the need for a system of care that improves buprenorphine treatment continuity of care for patients with opioid use disorder from emergency settings to community treatment providers.

Indexed as

BuprenorphineCOVID-19COVID-19 Drug TreatmentOpioid-Related DisordersPhysiciansAdultAnalgesics, OpioidHumansPrescriptionsUnited StatesAnalgesics, OpioidBuprenorphine

Identifiers

PMID35305851
PMCPMC9038689

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.