Evidence map›Paper›PMID 35305656›Full record

ArticleJournal of nanobiotechnology2022

Triamcinolone acetonide-loaded nanoparticles encapsulated by CD90

Yuanlong Li, Qingqiang Tu, Dongmei Xie, Shurui Chen, Kai Gao, Xiaochun Xu, Ziji Zhang, Xifan Mei

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Biomimetic materials for medical applications.Chinese medical journal · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Forkhead box O proteins in chondrocyte aging and diseases.Journal of orthopaedic translation · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. Multifunctional Nanozyme PDA-CrInternational journal of nanomedicine · 2025
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yuanlong Li *Department of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Qingqiang Tu *Department of Orthopedics, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Dongmei Xie *The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Shurui ChenDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Kai GaoDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Xiaochun XuThe Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Ziji ZhangDepartment of Orthopedics, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. zhangziji@mail.sysu.edu.cn.
Xifan MeiDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China. meixifan1971@163.com.
Jinzhou Medical University · CNThe First Affiliated Hospital, Sun Yat-sen University · CNSun Yat-sen University · CNThird Affiliated Hospital of Sun Yat-sen University · CN

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 82102667
6 · The paper itself

Abstract

backgroundOsteoarthritis (OA) is a highly prevalent human degenerative joint disorder that has long plagued patients. Glucocorticoid injection into the intra-articular (IA) cavity provides potential short-term analgesia and anti-inflammatory effects, but long-term IA injections cause loss of cartilage. Synovial mesenchymal stem cells (MSCs) reportedly promote cartilage proliferation and increase cartilage content.

methodsCD90

resultsThe CD90@MV membrane proteins were similar to that of CD90

conclusionThis study confirmed that T-CD90@NP promoted chondrocyte proliferation and anti-inflammation, improving the effects of a clinical glucocorticoid treatment plan.

Indexed as

NanoparticlesOsteoarthritisAnimalsAnti-Inflammatory AgentsCartilageHumansRabbitsRatsRegenerationTriamcinolone AcetonideAnti-Inflammatory AgentsTriamcinolone AcetonideAnti-inflammatoryBiomimetic nanoparticlesCartilage regenerationCD90+ MCSs-derived micro-vesicleOsteoarthritis

Identifiers

PMID35305656
PMCPMC8934450
OpenAlexW4220897802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.