Evidence map›Paper›PMID 35305633›Full record

ArticleBMC complementary medicine and therapies2022

Antimicrobial activity of Bacillus sp. isolated strains of wild honey.

Somayeh Hallaj-Nezhadi, Rasoul Hamdipour, Mohamad Shahrvirani, Roya Zare Tin, Florence Chapeland-Leclerc, Gwenael Ruprich-Robert, Solmaz Esnaashari, Babak Elyasi Far, Azita Dilmaghani

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  8. Pharmaceutics · 2023
    Review
  9. Article
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  11. Potential application of the probioticFrontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Somayeh Hallaj-NezhadiDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Rasoul HamdipourDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohamad ShahrviraniDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Roya Zare TinDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Florence Chapeland-LeclercInstitut Des Energies de Demain (IED), UMR 8236, Univ Paris Descartes, Sorbonne Paris Cité, F-75205, Paris, France.
Gwenael Ruprich-RobertInstitut Des Energies de Demain (IED), UMR 8236, Univ Paris Descartes, Sorbonne Paris Cité, F-75205, Paris, France.
Solmaz EsnaashariBiotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Babak Elyasi FarDepartment of Physiology and Pharmacology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
Azita DilmaghaniDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. dilmaghani.a@gmail.com.ORCID http://orcid.org/0000-0001-6556-8332
Tabriz University of Medical Sciences · IRUniversité Paris Cité · FRDezful University of Medical Sciences · IR

Funding

Tabriz University of Medical Sciences grant NO: 60598 and 58766
6 · The paper itself

Abstract

backgroundMulti-drug resistant bacteria hazards to the health of humans could be an agent in the destruction of human generation. Natural products of Bacillus species are the main source to access progressive antibiotics that can be a good candidate for the discovery of novel antibiotics. Wild honey as a valuable food has been used in medicine with antimicrobial effects.

objectiveBacillus strains isolated from wild honey were evaluated for the potential antimicrobial activity against human and plant bacterial and fungal pathogens.

methodsThree bacterial isolates were identified as strain Khuz-1 (98.27% similarity with Bacillus safensis subsp. Safensis strain FO-36b

resultsThe results indicated that B. rugosus strain Khuz-2 inhibited the growth of phytopathogenic and human fungal more effective than other ones. It seems that the strain Khuz-2 has a suitable antimicrobial and antifungal potential as a good candidate for further pharmaceutical research.

conclusionBased on the results of GC-MS, Pyrrolo [1,2-a] pyrazine-1,4-dion, hexahydro-3-(2-methylpropyle) (PPDHM) was the major compound for all strains which have a various pharmacological effect. Isolation and identification of beneficial bacteria from natural sources can play an important role in future pharmaceutical and industrial applications.

Indexed as

Anti-Infective AgentsBacillusHoneyFungiHumansRNA, Ribosomal, 16SAnti-Infective AgentsRNA, Ribosomal, 16SAntimicrobial activityBacillus sp.GC–MSHuman pathogensPhytopathogenic pathogenes

Identifiers

PMID35305633
PMCPMC8933914
OpenAlexW4220663549

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.