Evidence map›Paper›PMID 35305618›Full record

ArticleBMC veterinary research2022

Procoagulant and anticoagulant plasma indicators in diabetic dogs showing increased antithrombin III levels in canine diabetes mellitus.

Andrzej Milczak, Dagmara Winiarczyk, Stanisław Winiarczyk, Diana Bochyńska, Łukasz Adaszek, Mateusz Winiarczyk, Roman Lechowski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Andrzej MilczakDepartment and Clinic of Animal Internal Diseases, Sub-Department of Internal Diseases of Small Animals, University of Life Sciences in Lublin, Lublin, Poland.
Dagmara WiniarczykDepartment and Clinic of Animal Internal Diseases, Sub-Department of Internal Diseases of Small Animals, University of Life Sciences in Lublin, Lublin, Poland. winiarczykdm@gmail.com.
Stanisław WiniarczykDepartment of Epizootiology and Clinic of Infectious Diseases, University of Life Sciences in Lublin, Lublin, Poland.
Diana BochyńskaUniversity of Cambridge, Queen's Veterinary School, Cambridge, England.
Łukasz AdaszekDepartment of Epizootiology and Clinic of Infectious Diseases, University of Life Sciences in Lublin, Lublin, Poland.
Mateusz WiniarczykDepartment of Vitreoretinal Surgery, Medical University of Lublin, Lublin, Poland.
Roman LechowskiFaculty of Veterinary Medicine, Department of Small Animal Diseases with Clinic, Warsaw University of Life Sciences, Warsaw, Poland.
University of Life Sciences in Lublin · PLMedical University of Lublin · PLUniversity of Cambridge · GBWarsaw University of Life Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus (DM) often leads to dangerous thromboembolic complications in humans. DM is also a relatively common endocrinopathy of dogs. There is scarce information regarding procoagulant and anticoagulant plasma indicators in this disease. The aim of the study was to evaluate the levels of the selected plasma haemostatic parameters in dogs suffering from diabetes. The study group consisted of 20 dogs meeting all the inclusion criteria, with fasting glycaemia exceeding 11.1 mmol/l. The control group consisted of 15 healthy dogs presented for routine examination. An evaluation of the prothrombin time (PT); and fibrinogen, D-dimer and antithrombin III (ATIII) levels was performed.

resultsExcept for ATIII activity, the haemostatic parameter differences were not statistically significant. High values of ATIII activity were observed in 90% of diabetic dogs. On average, the values amounted to 166.6% and were 31.4% higher than those in the control group. The ATIII activity in the diabetic group was significantly higher than that in the control group (p = 0.0004).

conclusionsHere, we report elevated levels of ATIII in diabetic dogs. This finding may suggest the protective role of ATIII against potential thrombotic events. However, the exact role of ATIII in dog diabetes remains unclear.

Indexed as

Diabetes MellitusDog DiseasesAnimalsAnticoagulantsAntithrombin IIIDogsFibrinogenHemostasisAnticoagulantsAntithrombin IIIFibrinogenAntithrombin IIIBlood coagulationCanine diabetesDiabetesThrombosis

Identifiers

PMID35305618
PMCPMC8933892
OpenAlexW4220740491

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.