Evidence map›Paper›PMID 35305609›Full record

ArticleBMC pulmonary medicine2022

Understanding barriers to and strategies for medication adherence in COPD: a qualitative study.

Jacqueline O'Toole, Meera Krishnan, Kristin Riekert, Michelle N Eakin

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jacqueline O'TooleDivision of Pulmonary and Critical Care, Johns Hopkins University School of Medicine, Baltimore, USA. otoojc3@gmail.com.
Meera KrishnanDivision of Pulmonary and Critical Care, Johns Hopkins University School of Medicine, Baltimore, USA.
Kristin RiekertDivision of Pulmonary and Critical Care, Johns Hopkins University School of Medicine, Baltimore, USA.
Michelle N EakinDivision of Pulmonary and Critical Care, Johns Hopkins University School of Medicine, Baltimore, USA.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Longitudinal study of determinants of medication adherence in COPDR01HL128620 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI EAKIN, MICHELLE NUTTALL · 2016 to 2020
$3.5M
Medication plan concordance between patients and providers in COPD patientsF32HL143864 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI O' TOOLE, JACQUELINE · 2018 to 2019
$141k
NHLBI NIH HHS F32 HL143864NHLBI NIH HHS HL143864-01NHLBI NIH HHS R01 HL128620NHLBI NIH HHS R01 HL128620-02NHLBI NIH HHS T32 HL007534NIH HHS HL 007534
6 · The paper itself

Abstract

backgroundMedication adherence in chronic obstructive pulmonary disease (COPD) is low, though not enough is known about the factors that affect adherence in COPD. This study uses qualitative methods to understand the patient perspective on facilitators and barriers to medication adherence in COPD as well as patient-reported strategies for self-management of disease.

methodsSemi-structured interviews were conducted with 30 individuals (n = 30). Transcripts were analyzed using iterative qualitative coding by 2 independent coders, and codes were categorized using thematic analysis.

resultsChallenges with adherence reported were gaps in understanding, forgetfulness of the patient, physician availability, cost navigation, and overcoming substance use. Most commonly, the financial burden of COPD medications caused patients to source other countries to obtain medications, rely on sample medications collected during doctors' visits, and to alter medication dosage and frequency to extend the length of a prescription. Tools and resources reported by patients to support self-management of COPD included pharmacist assistance, physician office information, and community resources. Individuals further reported that the use of logs or diaries to track medication usage, visual or temporal cues to take medications, and support from family members were helpful in promoting adherence to their COPD medication regimen.

conclusionsMedication adherence in individuals with COPD is affected by challenges with self-management of disease and financial burden of medications. However, patients reported multiple tools and resources to support adherence. Physician recognition of these factors impacting self-management, as well as awareness of strategies to promote adherence and manage disease, may improve patient outcomes.

Indexed as

Pulmonary Disease, Chronic ObstructiveSelf-ManagementHumansMedication AdherenceQualitative ResearchAccess to careAdherenceBarriers to carePatient experienceRoutine

Identifiers

PMID35305609
PMCPMC8934480
OpenAlexW4221074869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.