ArticleVeterinary medicine and science2022
Expression profile analysis of sheep ovary after superovulation and estrus synchronisation treatment.
Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Reproductive Physiology, Genetic Architecture, and Management of Duolang Sheep Under Arid-Zone Production Systems: A Review.International journal of molecular sciences · 2026Review
- Study on the Function ofAnimals : an open access journal from MDPI · 2025Article
- Generation and assessment of high-quality fat-tailed dunnart oocytes following superovulation in prepubertal animals†.Biology of reproduction · 2025Article
- Uterine histomorphological and immunohistochemical investigation during the follicular phase of estrous cycle in Saidi sheep.BMC veterinary research · 2025Article
- Genome-wide association study reveals candidate genes for litter size and function validation ofFrontiers in veterinary science · 2025Article
- Article
- Exploration of transcriptional regulation network between buffalo oocytes and granulosa cells and its impact on different diameter follicles.BMC genomics · 2024Article
- Comparative Analysis of mRNA and lncRNA Expression Profiles in Testicular Tissue of Sexually Immature and Sexually Mature Mongolian Horses.Animals : an open access journal from MDPI · 2024Article
- Histological, immunohistochemical and serological investigations of the ovary during follicular phase of estrous cycle in Saidi sheep.BMC veterinary research · 2024Article
- Functional analysis of differentially expressed circular RNAs in sheep subcutaneous fat.BMC genomics · 2023Article
- Genome wide identification and characterization of fertility associated novel CircRNAs as ceRNA reveal their regulatory roles in sheep fecundity.Journal of ovarian research · 2023Article
- Insights into Transcriptomic Differences in Ovaries between Lambs and Adult Sheep after Superovulation Treatment.Animals : an open access journal from MDPI · 2023Article
- Detection of Candidate Genes Associated with Fecundity through Genome-Wide Selection Signatures of Katahdin Ewes.Animals : an open access journal from MDPI · 2023Article
- Expression profile analysis of sheep ovary after superovulation and estrus synchronisation treatment.Veterinary medicine and science · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Superovulation is a widely used reproductive technique in livestock production, but the mechanism of sheep's superovulation is not yet clear. Here, a method of superovulation and estrus synchronisation was used to treat female Duolang sheep. After treatment, there were significant differences in serum FSH and LH levels and the number of dominant follicles between the two groups of sheep. We identified a total of 5021 differentially expressed genes (11, 13 and 15 days after treatment) and performed RT-qPCR analysis to identify several mRNA expression levels. GO and KEGG enrichment analysis revealed that differentially expressed genes were involved in the regulation of signalling pathways of follicular development, cell cycle, material synthesis, energy metabolism, such as COL3A1, RPS8, ACTA2, RPL7 RPS6 and TNFAIP6 may play a key role in regulating the development of follicles. Our results show a comprehensive expression profile after superovulation and estrus synchronisation treatment. We provide the basis for further research on breeding techniques to improve the ovulation rate and birth rate of livestock.
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