Evidence map›Paper›PMID 35305115›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2022

Radiologic and clinical outcome of isolated fourth ventricle following post-hemorrhagic hydrocephalus in children.

Rida Salman, Thierry A G M Huisman, Stephen Kralik, Avner Meoded, Nilesh K Desai, Samuel G McClugage, Eugen Boltshauser, Gunes Orman

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rida SalmanEdward B. Singleton Department of Radiology, Fannin St, Texas Children's Hospital, Baylor College of Medicine, Suite 470, Houston, TX, USA.
Thierry A G M HuismanEdward B. Singleton Department of Radiology, Fannin St, Texas Children's Hospital, Baylor College of Medicine, Suite 470, Houston, TX, USA.
Stephen KralikEdward B. Singleton Department of Radiology, Fannin St, Texas Children's Hospital, Baylor College of Medicine, Suite 470, Houston, TX, USA.
Avner MeodedEdward B. Singleton Department of Radiology, Fannin St, Texas Children's Hospital, Baylor College of Medicine, Suite 470, Houston, TX, USA.
Nilesh K DesaiEdward B. Singleton Department of Radiology, Fannin St, Texas Children's Hospital, Baylor College of Medicine, Suite 470, Houston, TX, USA.
Samuel G McClugageDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Eugen BoltshauserDepartment of Pediatric Neurology, University Children's Hospital Zürich, Zurich, Switzerland.
Gunes OrmanEdward B. Singleton Department of Radiology, Fannin St, Texas Children's Hospital, Baylor College of Medicine, Suite 470, Houston, TX, USA. gxorman@texaschildrens.org.ORCID 0000-0003-2684-3957
Baylor College of Medicine · USUniversity Children's Hospital Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFew studies report radiologic and clinical outcome of post-hemorrhagic isolated fourth ventricle (IFV) with focus on surgical versus conservative management in neonates and children. Our aim is to investigate differences in radiological and clinical findings of IFV between patients who had surgical intervention versus patients who were treated conservatively.

methodsA retrospective analysis of patients diagnosed with IFV was performed. Data included demographics, clinical exam findings, surgical history, and imaging findings (dilated FV extent, supratentorial ventricle dilation, brainstem and cerebellar deformity, tectal plate elevation, basal cistern and cerebellar hemisphere effacement, posterior fossa upward/downward herniation).

resultsSixty-four (30 females) patients were included. Prematurity was 94% with 90% being < 28 weeks of gestation. Mean age at first ventricular shunt was 3.6 (range 1-19); at diagnosis of IFV, post-lateral ventricular shunting was 26.2 (1-173) months. Conservatively treated patients were 87.5% versus 12.5% treated with FV shunt/endoscopic fenestration. Severe FV dilation (41%), severe deformity of brainstem (39%) and cerebellum (47%) were noted at initial diagnosis and stable findings (34%, 47%, and 52%, respectively) were seen at last follow-up imaging. FV dilation (p = 0.0001) and upward herniation (p = 0.01) showed significant differences between surgery versus conservative management. No other radiologic or clinical outcome parameters were different between two groups.

conclusionOnly radiologic outcome results showed stable or normal FV dilation and stable or decreased upward herniation in the surgically treated group.

Indexed as

Fourth VentricleHydrocephalusBrain StemChildFemaleHumansInfant, NewbornMaleRetrospective StudiesTomography, X-Ray ComputedHydrocephalusIntraventricular hemorrhageIsolated fourth ventriclePrematurityTrapped fourth ventricle

Identifiers

PMID35305115
OpenAlexW4220926859

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.