ArticleMolecular psychiatry2022
Borderline personality disorder: associations with psychiatric disorders, somatic illnesses, trauma, and adverse behaviors.
Article in Molecular psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders.Nature genetics · 2026Pooled it
- The economic burden of Borderline Personality Disorder: direct and indirect costs, and evidence from evaluations of interventions.Frontiers in psychiatry · 2026Pooled it
- Personality disorders, violence and antisocial behaviour: updated systematic review and meta-regression analysis.The British journal of psychiatry : the journal of mental science · 2025Pooled it
- Trial
- Central nervous system acting medication used by young adults with borderline personality disorder in Sweden 2006-2019.Journal of psychopharmacology (Oxford, England) · 2026Article
- Holding the treatment frame: borderline features, personality functioning, and psychotherapy dropout in a youth mental health service.Research in psychotherapy (Milano) · 2026Article
- Borderline personality disorder and other psychiatric, somatic, and behavioral conditions: a nationwide family study.Translational psychiatry · 2026Article
- Childhood Traumatic Experiences and ICD-11 Model of Personality Disorders: a Study Among Croatian Psychiatric Patients.The Psychiatric quarterly · 2026Article
- Is the Prejudice Towards People With Borderline Personality Disorder Model Reflective of Lived Experience?International journal of mental health nursing · 2026Article
- Association of Borderline Personality Disorder with Physical Diseases and Mortality: A 16-Year Population-Based Electronic Health-Record Cohort Study in Hong Kong.Psychotherapy and psychosomatics · 2026Article
- Multidimensional Impulsivity Profile in Young Adults Aged 16 to 25 with Borderline Personality Disorder: A Study Based on the UPPS-P Model.Journal of clinical medicine · 2025Article
- Practice Assessment Tool for the Care of Patients With Borderline Personality Disorder.Focus (American Psychiatric Publishing) · 2025Article
- Burden of Disease of Borderline Personality Disorder: A Comprehensive Evaluation of Quality of Life and Societal Cost of Illness.Journal of clinical psychology · 2025Article
- Clinical Needs of Older Adults With Personality Disorders: Insights From State-Funded Mental Health Care Systems.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025Article
- Characteristics and outcomes of individuals screening positive for borderline personality disorder on an adult inpatient psychiatry unit: a cross-sectional study.BMC psychiatry · 2025Article
- Needs of Veterans With Personality Disorder Diagnoses in Community-Based Mental Health Care.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Article
- A predictive model of non-suicidal self-injury - a study based on the construction and validation of a nomogram.Frontiers in psychiatry · 2025Article
- Identity and Temporal Fragmentation in Borderline Personality Disorder: A Systematic Review.Brain sciences · 2024Review
- Article
- Identity Formation in Individuals between 16 and 25 Years Old with Borderline Personality Disorder.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
In one of the largest, most comprehensive studies on borderline personality disorder (BPD) to date, this article places into context associations between this diagnosis and (1) 16 different psychiatric disorders, (2) eight somatic illnesses, and (3) six trauma and adverse behaviors, e.g., violent crime victimization and self-harm. Second, it examines the sex differences in individuals with BPD and their siblings. A total of 1,969,839 Swedish individuals were identified from national registers. Cumulative incidence with 95% confidence intervals (CI) was evaluated after 5 years of follow-up from BPD diagnosis and compared with a matched cohort. Associations were estimated as hazard ratios (HR) with 95% CIs from Cox regression. 12,175 individuals were diagnosed with BPD (85.3% female). Individuals diagnosed with BPD had higher cumulative incidences and HRs for nearly all analyzed indicators, especially psychiatric disorders. Anxiety disorders were most common (cumulative incidence 95% CI 33.13% [31.48-34.73]). Other notable findings from Cox regressions include psychotic disorders (HR 95% CI 24.48 [23.14-25.90]), epilepsy (3.38 [3.08-3.70]), violent crime victimization (7.65 [7.25-8.06]), and self-harm (17.72 [17.27-18.19]). HRs in males and females with BPD had overlapping CIs for nearly all indicators. This indicates that a BPD diagnosis is a marker of vulnerability for negative events and poor physical and mental health similarly for both males and females. Having a sibling with BPD was associated with an increased risk for psychiatric disorders, trauma, and adverse behaviors but not somatic disorders. Clinical implications include the need for increased support for patients with BPD navigating the health care system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.