Evidence map›Paper›PMID 35304508›Full record

ArticleScientific reports2022

Assessing radiomics feature stability with simulated CT acquisitions.

Kyriakos Flouris, Oscar Jimenez-Del-Toro, Christoph Aberle, Michael Bach, Roger Schaer, Markus M Obmann, Bram Stieltjes, Henning Müller, Adrien Depeursinge, Ender Konukoglu

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kyriakos FlourisComputer Vision Lab, ETH Zurich, Zurich, Switzerland. kflouris@vision.ee.ethz.ch.
Oscar Jimenez-Del-ToroUniversity of Applied Sciences Western Switzerland (HES-SO) Valais, Sierre, Switzerland.
Christoph AberleClinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Michael BachClinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Roger SchaerUniversity of Applied Sciences Western Switzerland (HES-SO) Valais, Sierre, Switzerland.
Markus M ObmannClinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Bram StieltjesClinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Henning MüllerUniversity of Applied Sciences Western Switzerland (HES-SO) Valais, Sierre, Switzerland.
Adrien DepeursingeUniversity of Applied Sciences Western Switzerland (HES-SO) Valais, Sierre, Switzerland.
Ender KonukogluComputer Vision Lab, ETH Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical imaging quantitative features had once disputable usefulness in clinical studies. Nowadays, advancements in analysis techniques, for instance through machine learning, have enabled quantitative features to be progressively useful in diagnosis and research. Tissue characterisation is improved via the "radiomics" features, whose extraction can be automated. Despite the advances, stability of quantitative features remains an important open problem. As features can be highly sensitive to variations of acquisition details, it is not trivial to quantify stability and efficiently select stable features. In this work, we develop and validate a Computed Tomography (CT) simulator environment based on the publicly available ASTRA toolbox ( www.astra-toolbox.com ). We show that the variability, stability and discriminative power of the radiomics features extracted from the virtual phantom images generated by the simulator are similar to those observed in a tandem phantom study. Additionally, we show that the variability is matched between a multi-center phantom study and simulated results. Consequently, we demonstrate that the simulator can be utilised to assess radiomics features' stability and discriminative power.

Indexed as

Machine LearningTomography, X-Ray ComputedPhantoms, ImagingRetrospective Studies

Identifiers

PMID35304508
PMCPMC8933485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.