Evidence map›Paper›PMID 35304473›Full record

ArticleScientific reports2022

A contrastive learning approach for ICU false arrhythmia alarm reduction.

Yuerong Zhou, Guoshuai Zhao, Jun Li, Gan Sun, Xueming Qian, Benjamin Moody, Roger G Mark, Li-Wei H Lehman

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuerong ZhouXi'an Jiaotong University, Xi'an, China.
Guoshuai ZhaoXi'an Jiaotong University, Xi'an, China. guoshuai.zhao@xjtu.edu.cn.
Jun LiNanjing University of Science and Technology, Nanjing, China.
Gan SunChinese Academy of Sciences, Shenyang, China.
Xueming QianXi'an Jiaotong University, Xi'an, China.
Benjamin MoodyInstitute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Roger G MarkInstitute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Li-Wei H LehmanInstitute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. lilehman@mit.edu.

Funding

Research Resource for Complex Physiologic SignalsR01EB030362 · NIBIB · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GOLDBERGER, ARY LOUIS · 2020 to 2025
$5.8M
Critical Care Informatics: Ethical considerations around the use and sharing of health-related dataR01EB017205 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CELI, LEO ANTHONY G, MARK, ROGER GREENWOOD · 2014 to 2021
$3.8M
NIBIB NIH HHS R01 EB017205NIBIB NIH HHS R01 EB030362
6 · The paper itself

Abstract

The high rate of false arrhythmia alarms in Intensive Care Units (ICUs) can lead to disruption of care, negatively impacting patients' health through noise disturbances, and slow staff response time due to alarm fatigue. Prior false-alarm reduction approaches are often rule-based and require hand-crafted features from physiological waveforms as inputs to machine learning classifiers. Despite considerable prior efforts to address the problem, false alarms are a continuing problem in the ICUs. In this work, we present a deep learning framework to automatically learn feature representations of physiological waveforms using convolutional neural networks (CNNs) to discriminate between true vs. false arrhythmia alarms. We use Contrastive Learning to simultaneously minimize a binary cross entropy classification loss and a proposed similarity loss from pair-wise comparisons of waveform segments over time as a discriminative constraint. Furthermore, we augment our deep models with learned embeddings from a rule-based method to leverage prior domain knowledge for each alarm type. We evaluate our method using the dataset from the 2015 PhysioNet Computing in Cardiology Challenge. Ablation analysis demonstrates that Contrastive Learning significantly improves the performance of a combined deep learning and rule-based-embedding approach. Our results indicate that the final proposed deep learning framework achieves superior performance in comparison to the winning entries of the Challenge.

Indexed as

Clinical AlarmsArrhythmias, CardiacElectrocardiographyFalse Positive ReactionsHumansIntensive Care UnitsMonitoring, Physiologic

Identifiers

PMID35304473
PMCPMC8933571

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.