Evidence map›Paper›PMID 35303951›Full record

ArticleBMC research notes2022

Bacterial microbiome of faecal samples of naked mole-rat collected from the toilet chamber.

Kah-Ooi Chua, Iqra Fatima, Yin Yin Lau, Kar Wai Hong, Wai-Fong Yin, Andrei Mardaryev, Kok-Gan Chan, Chien-Yi Chang

Abstract read
In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kah-Ooi ChuaCentre for Research in Biotechnology for Agriculture, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Iqra FatimaCentre for Skin Sciences, School of Chemistry and Biosciences, University of Bradford, Bradford, BD7 1DP, UK.
Yin Yin LauDepartment of Biotechnology, Faculty of Applied Sciences, UCSI University Kuala Lumpur, 56000, Kuala Lumpur, Malaysia.
Kar Wai HongInternational Genome Centre, Jiangsu University, Zhenjiang, China.
Wai-Fong YinInstitute of Marine Sciences, Shantou University, Shantou, 515063, China.
Andrei MardaryevCentre for Skin Sciences, School of Chemistry and Biosciences, University of Bradford, Bradford, BD7 1DP, UK.
Kok-Gan ChanDepartment of Biotechnology, Faculty of Applied Sciences, UCSI University Kuala Lumpur, 56000, Kuala Lumpur, Malaysia. kokgan@um.edu.my.
Chien-Yi ChangSchool of Dental Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE2 4BW, UK. chienyi.chang@newcastle.ac.uk.ORCID http://orcid.org/0000-0003-3570-4019

Funding

Universiti Malaya FRGS grant FP022-2018AUniversiti Malaya UM-MOHE HIR Grant UM.C/625/1/HIR/MOHE/CHAN/01Universiti Malaya UM-MOHE HIR Grant UM.C/625/1/HIR/MOHE/CHAN/14/1
6 · The paper itself

Abstract

objectiveThe naked mole rats (NMRs, Heterocephalus glaber) are subterranean rodents that belong to the family Bathyergidae. They gained the attention of the scientific community for their exceptionally long lifespan of up to 30 years and have become an animal model of biomedical research on neurodegenerative diseases, aging and cancer. NMRs dig and survive in a maze of underground tunnels and chambers and demarcate toilet chambers for defecation and urination. Due to their coprophagic behaviours, we believed that the toilet chamber might play a role in maintaining optimal health of the NMRs. A 16S rRNA gene amplicon sequencing was performed to characterize the bacterial microbiome of faecal samples collected from the toilet chamber of a laboratory NMR colony.

resultsFour faecal samples were collected at different time points from the same toilet chamber of a laboratory NMR colony for analysis. The 16S rRNA gene amplicon sequencing revealed that bacterial phyla Firmicutes and Bacteroidetes were the dominant taxa in the bacterial microbiome of NMRs. The relative abundance of the bacterial taxa shifted substantially between time points, indicating a dynamic microbiome in the toilet chamber. The data provided an insight to the faecal microbiome of NMRs in the toilet chamber.

Indexed as

Bathroom EquipmentMicrobiotaAnimalsDisease Models, AnimalMole RatsRNA, Ribosomal, 16SRNA, Ribosomal, 16SBathyergidaCoprophagyHeterocephalus glaberMicrobiomeNaked mole-ratQIIME2RodentUniFrac

Identifiers

PMID35303951
PMCPMC8932300

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.