Evidence map›Paper›PMID 35303264›Full record

ArticleInternal and emergency medicine2022

Pharmaceutical pricing in Europe: time to take the right direction.

Livio Garattini, Bruno Finazzi, Pier Mannuccio Mannucci

Abstract read
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In one paragraph

Article in Internal and emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. New drugs and their performance 10 years after approval: a systematic analysis.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
  3. Article
  4. Modeling European health systems: a theoretical exercise.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Livio GarattiniInstitute for Pharmacological Research Mario Negri IRCCS, Ranica, BG, Italy.
Bruno FinazziInstitute for Pharmacological Research Mario Negri IRCCS, Ranica, BG, Italy.
Pier Mannuccio MannucciAngelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. piermannuccio.mannucci@policlinico.mi.it.ORCID 0000-0002-1915-3897

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A price stems from the intersection between supply and demand curves in any common market. However, there are special markets where consumers do not pay for goods directly, and prescription drugs are a well-known example in healthcare. Drugs are mainly funded by public expenditure in well-established welfare systems like those of the Western European countries. However, the present era of austerity in public funding has made financial resources scarce in most European nations. Currently, the leading tendency for pharmaceutical pricing in Europe is direct negotiation with pharma companies. However, these negotiations are administratively burdensome, with costs not necessarily offsetting savings. Moreover, since any trade negotiation implies some degree of confidentiality to be effective these strategies are scantily transparent. When prices are set for many products through unavoidably arbitrary decisions, the final consequence is an irrational allocation of financial resources. Here, we raise a proposal to restore a reasonable balance between public equity objectives of health authorities and private profit incentives of the pharma industry in Europe, switching from pricing to budgeting. The underlying rationale of our proposal is to stop setting arbitrary prices in a context of market failure.

Indexed as

Drug CostsDrug IndustryCosts and Cost AnalysisEuropeHumansPharmaceutical PreparationsPharmaceutical PreparationsBudgetEuropePharmaceuticalPrice

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.