Evidence map›Paper›PMID 35303253›Full record

ReviewCurrent oncology reports2022

Helping Patients Understand and Cope with BRCA Mutations.

Sukh Makhnoon, Banu Arun, Isabelle Bedrosian

Abstract readReview
In one paragraph

Review in Current oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Lights genes action: Video strategy forGynecologic oncology reports · 2026
    Article
  3. Navigating the healthcare system with aGynecologic oncology reports · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sukh MakhnoonDepartment of Behavioral Science, UT MD Anderson Cancer Center, Dan L. Duncan Building, 1515 Holcombe Blvd, Unit 1330, Houston, TX, 77030, USA. smakhnoon@mdanderson.org.ORCID 0000-0002-3380-3833
Banu ArunDepartment of Breast Medical Oncology, UT MD Anderson Cancer Center, Houston, TX, 77030, USA.
Isabelle BedrosianDepartment of Breast Surgical Oncology, UT MD Anderson Cancer Center, Houston, TX, 77030, USA.

Funding

Multilevel investigation of uncertain and reclassified genomic variants in clinical oncologyK99CA256216 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MAKHNOON, SUKH · 2021 to 2022
$216k
NCI NIH HHS K99 CA256216
6 · The paper itself

Abstract

purpose of reviewIndividuals carrying germline mutations in BRCA1/2 have unique psychosocial and educational needs that must be met to ensure informed clinical decision-making. In this review, we highlight the strategies used in clinical practice to support patients' needs as well as currently available pre- and post-disclosure support interventions. RECENT

findingsClinical risk communication is complicated by the uncertainty associated with gene penetrance, inconclusive results, variable effectiveness of surgical and screening interventions, and inadequate awareness of clinical genetics. Interventions to support patients' psychosocial needs, and strategies for effective and scalable clinical risk communication are in routine use and largely effective at meeting patients' needs. Research is underway to develop newer supportive resources; however, the inadequate representation of all mutation carriers persists. Effective clinical risk communication strategies, decision support aids, written educational materials, and supportive psychosocial tools can together have a large impact on meeting BRCA carriers' supportive needs.

Indexed as

Adaptation, PsychologicalBreast NeoplasmsBRCA1 ProteinFemaleHumansMutationBRCA1 ProteinBRCA1/2Clinical decision-makingCopingGenetic educationPsychosocial support

Identifiers

PMID35303253
PMCPMC8930486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.