Evidence map›Paper›PMID 35303205›Full record

ArticleMolecular imaging and biology2022

Evaluation of [

Saeka Shimochi, Thomas Keller, Ella Kujala, Joonas Khabbal, Johan Rajander, Eliisa Löyttyniemi, Olof Solin, Pirjo Nuutila, Shigehiko Kanaya, Emrah Yatkin and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular imaging and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Up-and-coming Radiotracers for Imaging Pain Generators.Seminars in musculoskeletal radiology · 2023
    Article
  3. Evaluation ofJournal of clinical medicine · 2022
    Article
  4. Pharmaceutics · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Saeka ShimochiTurku PET Centre, University of Turku, Turku, Finland.
Thomas KellerTurku PET Centre, University of Turku, Turku, Finland.
Ella KujalaCentral Animal Laboratory, University of Turku, Turku, Finland.
Joonas KhabbalCentral Animal Laboratory, University of Turku, Turku, Finland.
Johan RajanderAccelerator Laboratory, Turku PET Centre, Åbo Akademi University, Turku, Finland.
Eliisa LöyttyniemiDepartment of Biostatistics, University of Turku, Turku, Finland.
Olof SolinTurku PET Centre, University of Turku, Turku, Finland.
Pirjo NuutilaTurku PET Centre, University of Turku, Turku, Finland.
Shigehiko KanayaNara Institute of Science and Technology, Ikoma City, Japan.
Emrah YatkinCentral Animal Laboratory, University of Turku, Turku, Finland.
Tove J Grönroos *Turku PET Centre, University of Turku, Turku, Finland.
Hidehiro Iida *Turku PET Centre, University of Turku, Turku, Finland. hidehiro.iida@utu.fi.ORCID 0000-0002-7914-3068
University of Turku · FIÅbo Akademi University · FINara Institute of Science and Technology · JPTurku University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecent studies have linked activated spinal glia to neuropathic pain. Here, using a positron emission tomography (PET) scanner with high spatial resolution and sensitivity, we evaluated the feasibility and sensitivity of N,N-diethyl-2-(2-(4-([ PROCEDURES: Neuropathic pain was induced in rats (n = 20) by PSNL, and pain sensation tests were conducted before surgery and 3 and 7 days post-injury. On day 7, in vivo PET imaging and ex vivo autoradiography were performed using [

resultsMechanical allodynia was confirmed in the PSNL rats from day 3 through day 7. Ex vivo autoradiography showed a higher lesion-to-background uptake with [

conclusions[

Indexed as

MicrogliaNeuralgiaAnimalsFluorine RadioisotopesPositron-Emission TomographyPyrazolesPyrimidinesRatsSpinal CordTissue DistributionFluorine RadioisotopesPyrazolesPyrimidines[11C]PK11195[18F]F-DPAMicrogliaNeuropathic painPositron emission tomography (PET)Spinal cordTranslocator protein 18 kDa (TSPO)

Identifiers

PMID35303205
PMCPMC9296394
OpenAlexW4221137817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.