Evidence map›Paper›PMID 35303184›Full record

ArticleCurrent microbiology2022

Carvacrol Enhances the Antimicrobial Potency of Berberine in Bacillus subtilis.

Basak Atas, Cemile Selin Aksoy, Fatma Gizem Avci, Nihat Alpagu Sayar, Kutlu Ulgen, Elif Ozkirimli, Berna Sariyar Akbulut

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Basak AtasBioengineering Department, Marmara University, Kadikoy, 34722, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-9959-6964
Cemile Selin AksoyBioengineering Department, Marmara University, Kadikoy, 34722, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-3348-8201
Fatma Gizem AvciBioengineering Department, Uskudar University, Uskudar, 34662, Istanbul, Turkey.
Nihat Alpagu SayarBioengineering Department, Marmara University, Kadikoy, 34722, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-8895-1489
Kutlu UlgenChemical Engineering Department, Bogazici University, Bebek, 34342, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-3668-3467
Elif OzkirimliChemical Engineering Department, Bogazici University, Bebek, 34342, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-3206-8427
Berna Sariyar AkbulutBioengineering Department, Marmara University, Kadikoy, 34722, Istanbul, Turkey. berna.akbulut@marmara.edu.tr.ORCID http://orcid.org/0000-0002-4455-1192
Marmara University · TRBoğaziçi University · TRÜsküdar University · TR

Funding

Marmara Üniversitesi FEN-A-081117-0626Marmara Üniversitesi FEN-CYLP-120418-0166
6 · The paper itself

Abstract

The essential oil carvacrol from oregano displays a wide range of biological activities among which is found the inhibition of efflux pumps. Thus, using carvacrol, the current work undertook the effort to potentiate the antimicrobial activity of berberine, a natural product with limited antimicrobial efficacy due to its efflux. Following the selection of concentrations for the combinatorial treatments, guided by checkerboard microtiter plate assay and growth experiments, ethidium bromide accumulation assay was used to find that 25 μg mL

Indexed as

Anti-Infective AgentsBerberineBacillus subtilisCymenesHumansAnti-Infective AgentsBerberinecarvacrolCymenes

Identifiers

PMID35303184
OpenAlexW4220656788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.