Evidence map›Paper›PMID 35303160›Full record

Trial reportEuropean journal of applied physiology2022

The acute, systemic effects of aerobic exercise in recently concussed adolescent student-athletes: preliminary findings.

P R Worts, J R Mason, S O Burkhart, M A Sanchez-Gonzalez, J-S Kim

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03575455 (The Short- And Long-Term Effects Of Submaximal Aerobic Exercise On Recovery Following Sport-Related Concussion In High School Student-Athletes), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03575455 nacompletednot on this map

The Short- And Long-Term Effects Of Submaximal Aerobic Exercise On Recovery Following Sport-Related Concussion In High School Student-Athletes

TypeinterventionalSponsorFlorida State UniversityRan2017 to 2020Enrolled30ConditionsSport-related ConcussionArmsExercise
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Scoping review: Intervention for ocular motor disorders in children and adults with mild traumatic brain injury.Optometry and vision science : official publication of the American Academy of Optometry · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Autonomic dysfunction and exercise intolerance in concussion: a scoping review.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

P R WortsTallahassee Orthopedic Clinic, Tallahassee, FL, USA. Phillip.Worts@tlhoc.com.ORCID http://orcid.org/0000-0002-5571-5404
J R MasonDepartment of Occupational Therapy, University of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0001-7452-8578
S O BurkhartChildren's Health Andrews Institute, Plano, TX, USA.ORCID http://orcid.org/0000-0002-0992-8740
M A Sanchez-GonzalezLake Erie College of Osteopathic Medicine, Bradenton, FL, USA.ORCID http://orcid.org/0000-0002-7585-708X
J-S KimDepartment of Nutrition and Integrative Physiology, Florida State University, Tallahassee, FL, USA.ORCID https://orcid.org/0000-0003-0405-2281
Florida State University · USAndrews Institute for Orthopaedics & Sports Medicine · USLake Erie College of Osteopathic Medicine · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesExamine the acute effects (pre-, during, post-intervention) of two different intensities of aerobic exercise or rest on autonomic, oculomotor, and vestibular function and symptom burden in patients with a recent sport-related concussion (SRC) and compare their responses to sex-matched, age-stratified, non-concussed (HEALTHY) student-athletes.

methodsStudent-athletes between the ages of 13 and 18 that presented to the sports medicine clinic within Day 3-7 post-SRC and from local schools were recruited for a randomized controlled trial (RCT). The participants were administered the Vestibular/Ocular Motor Screening (VOMS), King-Devick (K-D), and Post-Concussion Symptom Scale (PCSS) before and after the intervention. Heart rate variability (HRV) and mean arterial pressure (MAP) were collected before, during, and after the intervention. The intervention was either a single, 20-min session of treadmill walking at 40% (40HR) or 60% of age-predicted max heart rate (60HR), or seated, rest (NOEX).

results30 participants completed the intervention with the SRC group treated 4.5 ± 1.3 days post-injury. Pre-exercise HRV and MAP were significantly different (p's < 0.001) during treatment but returned to pre-exercise values within 5 min of recovery in both the SRC and HEALTHY groups. Both the SRC and HEALTHY groups exhibited similar reductions pre- to post-intervention for symptom severity and count (p's < 0.05), three VOMS items (p's < 0.05) but not K-D time.

conclusionsTo date, this is the first adolescent RCT to report the acute, systemic effects of aerobic exercise on recently concussed adolescent athletes. The interventions appeared safe in SRC participants, were well-tolerated, and provided brief therapeutic benefit.

trial registrationClinicaltrials.gov Identifier NCT03575455.

Indexed as

Athletic InjuriesBrain ConcussionAdolescentAthletesExerciseHumansStudentsActive rehabilitationExertionMild traumatic brain injurymTBIPediatricsPhysical activity

Identifiers

PMID35303160
OpenAlexW4220908443

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.