Evidence map›Paper›PMID 35303143›Full record

ReviewBioprocess and biosystems engineering2022

Lab-scale photobioreactor systems: principles, applications, and scalability.

Philipp Benner, Lisa Meier, Annika Pfeffer, Konstantin Krüger, José Enrique Oropeza Vargas, Dirk Weuster-Botz

Abstract readReview
In one paragraph

Review in Bioprocess and biosystems engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Population Dynamics Analysis ofPlants (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Improving productivity of citramalate from COBiotechnology for biofuels and bioproducts · 2024
    Article
  14. Review
  15. Towards industrial biological hydrogen production: a review.World journal of microbiology & biotechnology · 2023
    Review
  16. Laboratory- and Pilot-Scale Cultivation ofLife (Basel, Switzerland) · 2023
    Article
  17. Optimization of COLife (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Philipp BennerDepartment of Energy and Process Engineering, Chair of Biochemical Engineering, Technical University of Munich, TUM School of Engineering and Design, Boltzmannstraße 15, 85748, Garching, Germany.ORCID http://orcid.org/0000-0001-7675-0383
Lisa MeierTechnical University of Munich, TUM School of Engineering and Design, Boltzmannstraße 15, 85748, Garching, Germany.
Annika PfefferTechnical University of Munich, TUM School of Engineering and Design, Boltzmannstraße 15, 85748, Garching, Germany.
Konstantin KrügerTechnical University of Munich, TUM School of Engineering and Design, Boltzmannstraße 15, 85748, Garching, Germany.
José Enrique Oropeza VargasTechnical University of Munich, TUM School of Engineering and Design, Boltzmannstraße 15, 85748, Garching, Germany.
Dirk Weuster-BotzDepartment of Energy and Process Engineering, Chair of Biochemical Engineering, Technical University of Munich, TUM School of Engineering and Design, Boltzmannstraße 15, 85748, Garching, Germany. dirk.weuster-botz@tum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phototrophic microorganisms that convert carbon dioxide are being explored for their capacity to solve different environmental issues and produce bioactive compounds for human therapeutics and as food additives. Full-scale phototrophic cultivation of microalgae and cyanobacteria can be done in open ponds or closed photobioreactor systems, which have a broad range of volumes. This review focuses on laboratory-scale photobioreactors and their different designs. Illuminated microtiter plates and microfluidic devices offer an option for automated high-throughput studies with microalgae. Illuminated shake flasks are used for simple uncontrolled batch studies. The application of illuminated bubble column reactors strongly emphasizes homogenous gas distribution, while illuminated flat plate bioreactors offer high and uniform light input. Illuminated stirred-tank bioreactors facilitate the application of very well-defined reaction conditions. Closed tubular photobioreactors as well as open photobioreactors like small-scale raceway ponds and thin-layer cascades are applied as scale-down models of the respective large-scale bioreactors. A few other less common designs such as illuminated plastic bags or aquarium tanks are also used mainly because of their relatively low cost, but up-scaling of these designs is challenging with additional light-driven issues. Finally, this review covers recommendations on the criteria for photobioreactor selection and operation while up-scaling of phototrophic bioprocesses with microalgae or cyanobacteria.

Indexed as

CyanobacteriaMicroalgaeBiomassCarbon DioxideHumansPhotobioreactorsCarbon DioxideLab-scale reactorsMicroalgaePhotobioreactorScale-up

Identifiers

PMID35303143
PMCPMC9033726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.