SynthesisJournal of clinical oncology : official journal of the American Society of Clinical Oncology2022
Risk of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy: A Systematic Review and Individual Patient Data Meta-Analysis.
Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph
Synthesis in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
15.5field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Pathogenesis of peritoneal high-grade serous carcinoma after risk-reducing surgery: a systematic review.The journal of pathology. Clinical research · 2025Pooled it
- Intergroup statement: opportunistic salpingectomy-molecular pathology, clinical outcomes and implications for practice (German Ovarian Cancer Commission, the North-Eastern German Society of Gynecologic Oncology (NOGGO), AGO Austria and AGO Swiss).Archives of gynecology and obstetrics · 2025Guideline
- Incidence of pelvic high-grade serous carcinoma after isolated STIC diagnosis: A systematic review of the literature.Frontiers in oncology · 2022Pooled it
- Tubal epithelial alterations: evolving concepts.Journal of gynecologic oncology · 2026Review
- Rethinking ovarian cancer III: the past decade and future directions.Nature reviews. Cancer · 2026Review
- Management of incidental STIC lesions with and without BRCA mutations: a survey of current clinical practice in Austria, Germany, and Switzerland.Archives of gynecology and obstetrics · 2026Article
- A retrospective analysis of risk-reducing salpingo-oophorectomy performed in women diagnosed with hereditary breast and ovarian cancer at our institution.Hereditary cancer in clinical practice · 2026Article
- Ovarian cancer.Nature reviews. Disease primers · 2026Review
- Oncologic outcomes of incidental serous tubal intraepithelial carcinoma and associated high-grade serous carcinoma in high-risk patients undergoing risk-reducing surgery.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2026Article
- Review
- The uterine secretome initiates growth of gynecologic tissues in ectopic locations: re-evaluating the evidence.Pathology oncology research : POR · 2026Review
- Inflammasome activation contributes to cisplatin resistance in ovarian cancer.Journal of ovarian research · 2025Article
- From Fallopian Tube to Ovarian Cancer: Understanding the Evaluation and Management of Serous Tubal Intraepithelial Carcinoma Lesions.Current treatment options in oncology · 2025Review
- Cancer of the ovary, fallopian tube, and peritoneum: 2025 update.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Review
- Clinical outcome and pattern of care for isolated or incidental serous tubal intraepithelial carcinoma: a multicenter retrospective cohort study.Journal of gynecologic oncology · 2025Article
- Integration of cell-type resolved spatial proteomics and transcriptomics reveals novel mechanisms in early ovarian cancer.medRxiv : the preprint server for health sciences · 2025Article
- Integrated Spatial Analysis of Ovarian Precancerous Lesions.bioRxiv : the preprint server for biology · 2025Article
- Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma.Cancer discovery · 2025Article
- Adenocarcinoma of Müllerian origin developed 22 years after Salpingo-oophorectomy in a woman with BRCA1 mutation: a thought about modification of chemotherapy dose and peritoneal resection.Oxford medical case reports · 2025Article
- First Analysis of the Incidence of Serous Tubal Intraepithelial Carcinoma (STIC) in Germany - Evaluation of the Cancer Registry of the Federal State of Rhineland-Palatinate from 2016 to 2023.Geburtshilfe und Frauenheilkunde · 2025Article
Corrections and comments
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Authors and funding
22 authors at 10 institutions in 5 countries.
Miranda P SteenbeekRadboud University Medical Center, Radboud Institute for Health Sciences, Department of Obstetrics and Gynaecology, Nijmegen, the Netherlands.ORCID 0000-0001-6097-1579
Majke H D van BommelRadboud University Medical Center, Radboud Institute for Health Sciences, Department of Obstetrics and Gynaecology, Nijmegen, the Netherlands.ORCID 0000-0002-7562-9861
Johan BultenRadboud University Medical Center, Department of Pathology, Nijmegen, the Netherlands.
Julia A HulsmannRadboud University Medical Center, Radboud Institute for Health Sciences, Department of Obstetrics and Gynaecology, Nijmegen, the Netherlands.ORCID 0000-0002-1273-9692
Joep BogaertsRadboud University Medical Center, Department of Pathology, Nijmegen, the Netherlands.ORCID 0000-0003-0772-6712
Christine GarciaKaiser Permanente Northern California, Division of Gynecologic Oncology San Francisco, San Francisco CA.
Han T CunDepartment of Gynecologic Oncology and Reproductive Medicine, University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-1465-2267
Karen H LuDepartment of Gynecologic Oncology and Reproductive Medicine, University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-5317-9927
Heleen J van BeekhuizenErasmus MC Cancer Center, University Medical Center Rotterdam, Department of Gynecological Oncology, Rotterdam, the Netherlands.ORCID 0000-0001-8899-7412
Lucas MinigGynecologic Oncology Unit, IMED Hospitales, Valencia, Spain.ORCID 0000-0001-7648-5604
Katja N GaarenstroomLeiden University Medical Center, Department of Obstetrics and Gynecology, Leiden, the Netherlands.
Marielle NobbenhuisThe Royal Marsden NHS Foundation Trust, Department of Gynaecology, London, England.
Mateja KrajcInstitute of Oncology Ljubljana, Department of Clinical Genetics, Ljubljana, Slovenia.ORCID 0000-0003-0605-2592
Vilius RudaitisVilnius University Faculty of Medicine, Clinic of Obstetrics and Gynecology, Vilnius, Lithuania.
Barbara M NorquistUniversity of Washington, Division of Gynecologic Oncology, Seattle, WA.ORCID 0000-0001-5992-7845
Elizabeth M SwisherUniversity of Washington, Division of Gynecologic Oncology, Seattle, WA.
Marian J E MouritsUniversity Medical Center Groningen, University of Groningen, Department of Gynecologic Oncology, Groningen, the Netherlands.ORCID 0000-0003-2385-2639
Leon F A G MassugerRadboud University Medical Center, Radboud Institute for Health Sciences, Department of Obstetrics and Gynaecology, Nijmegen, the Netherlands.
Nicoline HoogerbruggeRadboud University Medical Center, Department of Human Genetics, Nijmegen, the Netherlands.ORCID 0000-0003-2393-8141
Rosella P M G HermensRadboud University Medical Center, Radboud Institute for Health Sciences, Scientific Institute for Quality of Healthcare, Nijmegen, the Netherlands.ORCID 0000-0001-7624-7120
Joanna IntHoutRadboud University Medical Center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, the Netherlands.
Joanne A de HulluRadboud University Medical Center, Radboud Institute for Health Sciences, Department of Obstetrics and Gynaecology, Nijmegen, the Netherlands.
Radboud University Nijmegen · NLThe University of Texas MD Anderson Cancer Center · USUniversity of Washington · USErasmus MC Cancer Institute · NLInstitute of Oncology Ljubljana · SIKaiser Permanente · USLeiden University Medical Center · NLRoyal Marsden NHS Foundation Trust · GBUniversity Medical Center Groningen · NLVilnius University · LT
Funding
Training of Academic Gynecologic OncologistsT32CA101642 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ANIL K SOOD, Kathleen Schmeler · 2005 to 2026
$9.2MNCI NIH HHS T32 CA101642
Abstract
purposeAfter risk-reducing salpingo-oophorectomy (RRSO),
methodsUnpublished data from three centers were supplemented by studies identified in a systematic review of EMBASE, MEDLINE, and the Cochrane library describing women with a
resultsFrom 17 studies, individual patient data were available for 3,121 women, of whom 115 had a STIC at RRSO. The estimated hazard ratio to develop PC during follow-up in women with STIC was 33.9 (95% CI, 15.6 to 73.9),
conclusion
Indexed as
Cystadenocarcinoma, SerousFallopian Tube NeoplasmsOvarian NeoplasmsPeritoneal NeoplasmsFemaleHeterozygoteHumansMutationOvariectomySalpingo-oophorectomy
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.