Evidence map›Paper›PMID 35302863›Full record

ReviewScience immunology2022

Transforming growth factor-β1 in regulatory T cell biology.

Joshua M Moreau, Maria Velegraki, Chelsea Bolyard, Michael D Rosenblum, Zihai Li

Open access · greenAbstract readReview
In one paragraph

Review in Science immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 156 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed, 1 pooled it
17.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

156 citing papers in PubMed, 1 synthesis or guideline pooled it, 221 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Regulatory T cells in cancer and inflammation.Signal transduction and targeted therapy · 2026
    Review
  16. Article
  17. Review
  18. Ferroptosis-induced immune modulation: a new frontier in glioblastoma therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  19. Article
  20. Article

96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joshua M MoreauDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.ORCID 0000-0002-1227-1508
Maria VelegrakiPelotonia Institute for Immuno-Oncology, the Ohio State University Comprehensive Cancer Center-James Cancer Hospital, Columbus, OH, USA.ORCID 0000-0003-3062-9777
Chelsea BolyardPelotonia Institute for Immuno-Oncology, the Ohio State University Comprehensive Cancer Center-James Cancer Hospital, Columbus, OH, USA.
Michael D RosenblumDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.ORCID 0000-0002-0462-5732
Zihai LiPelotonia Institute for Immuno-Oncology, the Ohio State University Comprehensive Cancer Center-James Cancer Hospital, Columbus, OH, USA.ORCID 0000-0003-4603-927X
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · USUniversity of California, San Francisco · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Molecular chaperones and immune toleranceR01AI077283 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LI, ZIHAI · 2009 to 2021
$3.7M
Targeting GRP94-TGF-beta Pathway for Cancer Immunotherapy SupplementR01CA262069 · NCI · OHIO STATE UNIVERSITY · PI LI, ZIHAI · 2021 to 2025
$2.9M
NCI NIH HHS P30 CA016058NCI NIH HHS R01 CA262069NIAID NIH HHS R01 AI077283
6 · The paper itself

Abstract

Transforming growth factor-β1 (TGF-β1) is inextricably linked to regulatory T cell (T

Indexed as

T-Lymphocytes, RegulatoryTransforming Growth Factor beta1BiologyImmune ToleranceMembrane ProteinsMembrane ProteinsTransforming Growth Factor beta1

Identifiers

PMID35302863
PMCPMC10552796
OpenAlexW4220854577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.