Evidence map›Paper›PMID 35302856›Full record

ArticleScience advances2022

Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli.

Tobias Staudigl, Juri Minxha, Adam N Mamelak, Katalin M Gothard, Ueli Rutishauser

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Neural Bases of Collective Social Behavior and Group Interactions across Species.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
  4. Saccade-related LFP power transients in the primate amygdala and hippocampus linked to the perception of social status.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Mind's eye: Saccade-related evoked potentials support visual encoding in humans.medRxiv : the preprint server for health sciences · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Tobias StaudiglDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0003-2885-1280
Juri MinxhaDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0003-4942-3269
Adam N MamelakDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-4245-6431
Katalin M GothardDepartment of Physiology, College of Medicine, University of Arizona, Tucscon, AZ 85724, USA.ORCID 0000-0001-9642-2985
Ueli RutishauserDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-9207-7069
California Institute of Technology · USCedars-Sinai Medical Center · USUniversity of Arizona · US

Funding

The Impact of Oxytocin on the Neural Representation Social Stimuli P50MH100023 · NIMH · EMORY UNIVERSITY · PI YOUNG, LARRY J · 2013 to 2022
$21.8M
Neuronal mechanisms of human episodic memoryU01NS117839 · NINDS · CEDARS-SINAI MEDICAL CENTER · PI MAMELAK, ADAM NATHANIEL, RUTISHAUSER, UELI · 2020 to 2024
$7.8M
Single-neuron mechanisms of executive control of long-term memory processes in humansR01MH110831 · NIMH · CEDARS-SINAI MEDICAL CENTER · PI RUTISHAUSER, UELI · 2016 to 2020
$2.2M
The Role of the Primate Amygdala in Social and Affective TouchR01MH121009 · NIMH · UNIVERSITY OF ARIZONA · PI GOTHARD, KATALIN M · 2019 to 2022
$2.1M
NIMH NIH HHS P50 MH100023NIMH NIH HHS R01 MH110831NINDS NIH HHS U01 NS117839
6 · The paper itself

Abstract

Humans predominantly explore their environment by moving their eyes. To optimally communicate and process visual information, neural activity needs to be coordinated with the execution of eye movements. We investigated the coordination between visual exploration and interareal neural communication by analyzing local field potentials and single neuron activity in patients with epilepsy. We demonstrated that during the free viewing of images, neural communication between the human amygdala and hippocampus is coordinated with the execution of eye movements. The strength and direction of neural communication and hippocampal saccade-related phase alignment were strongest for fixations that landed on human faces. Our results argue that the state of the human medial temporal lobe network is selectively coordinated with motor behavior. Interareal neural communication was facilitated for social stimuli as indexed by the category of the attended information.

Indexed as

Eye MovementsSaccadesHippocampusHumansTemporal Lobe

Identifiers

PMID35302856
PMCPMC8932656
OpenAlexW4220777307

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.