SynthesisJournal of diabetes investigation2022
Obstructive sleep apnea, prediabetes and progression of type 2 diabetes: A systematic review and meta-analysis.
Synthesis in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 7 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Integrating Social and Clinical Determinants of Pre-Eclampsia: A Hierarchical Systematic Review and Conceptual Framework for Prevention.BJOG : an international journal of obstetrics and gynaecology · 2026Pooled it
- The impact of sleep disturbances in individuals with comorbid diabetes and chronic kidney disease: a systematic review.Sleep & breathing = Schlaf & Atmung · 2025Pooled it
- Prevalence of obstructive sleep apnea in pakistan: a systematic review and meta-analysis of observational studies.Sleep & breathing = Schlaf & Atmung · 2025Pooled it
- Association between obstructive sleep apnea syndrome and type1/type2 diabetes mellitus: A systematic review and meta-analysis.Journal of diabetes investigation · 2025Pooled it
- Sleep disorders and associated factors among medical students in the Middle East and North Africa: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- A systematic review of the methodology for examining the relationship between obstructive sleep apnea and type two diabetes mellitus.Frontiers in endocrinology · 2024Pooled it
- Obstructive sleep apnea, prediabetes and progression of type 2 diabetes: A systematic review and meta-analysis.Journal of diabetes investigation · 2022Pooled it
- Chronicity and comorbidities: Is estimated longer duration of obstructive sleep apnoea linked to higher cardiometabolic risk?Lung India : official organ of Indian Chest Society · 2026Article
- Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024).World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Combination of dysfunctional beliefs about sleep and excessive daytime sleepiness as a psychobehavioral characteristic of comorbid insomnia and sleep apnea.Scientific reports · 2026Article
- Real-world predictors of progression to type 2 diabetes among adults with prediabetes.Diabetes, obesity & metabolism · 2026Article
- Mechanisms Linking Sleep-Disordered Breathing and Cardiometabolic Disease Risk.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Association between metabolic dysfunction-associated steatotic liver disease and obstructive sleep apnea: a nationwide retrospective cohort study.Scientific reports · 2026Article
- Development and Validation of Prediction Models for Severe Obstructive Sleep Apnea Based on Periodic Health Examinations.The clinical respiratory journal · 2026Article
- Patient Perspectives of a Sleep Apnea Treatment Adherence Intervention Adapted for Persons with Traumatic Brain Injury.Brain injury · 2025Article
- Molecular Biomarkers and Therapeutic Approach of Patients with Diabetes and Obstructive Sleep Apnea.International journal of molecular sciences · 2025Review
- Obstructive sleep apnea mediates genetic risk of Diabetes Mellitus in Hispanic and Latino communities.Communications medicine · 2025Article
- Association between visceral fat area and heart rate variability in high altitude migrants with OSA: the mediating effect of insulin resistance.Lipids in health and disease · 2025Article
- Plain Language Summary: Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults.American journal of lifestyle medicine · 2025Article
- Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults: A Clinical Practice Guideline From the American College of Lifestyle Medicine.American journal of lifestyle medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
AIMS/
introductionObstructive sleep apnea (OSA) is related to prediabetes and diabetes. Whether patients with OSA have a higher risk of prediabetes/diabetes remains unclear. We aimed to carry out a meta-analysis of published studies to evaluate the relationships between OSA and prediabetes and diabetes, and the impact of the severity of OSA on diabetes. MATERIALS AND
methodsThe PubMed, EMBASE and Cochrane databases were searched from January 2011 to July 2021. The associations between OSA and impaired fasting glucose, impaired glucose tolerance, impaired glucose regulation and diabetes mellitus were analyzed. We estimated the pooled odds ratios using fixed or random effects models. We included 25 studies comprising a total of 154,948 patients with OSA and risk factors for prediabetes/diabetes (20 and 16, respectively) in the analysis.
resultsOSA was associated with a higher risk of impaired fasting glucose, impaired glucose tolerance, impaired glucose regulation and diabetes mellitus in the cohort studies and cross-sectional studies. The pooled odds ratios were 2.34 (95% confidence interval [CI] 1.16-4.72), 1.58 (95% CI 1.15-2.15), 1.65 (95% CI 1.12-2.42), 2.15 (95% CI 1.68-2.75) and 3.62 (95% CI 2.75-4.75), respectively. Subgroup analyses were based on the proportions of men and women. The results showed that OSA was a risk factor, and there was no significant difference between the two groups. The risk of diabetes increased with the severity of OSA.
conclusionsThe risk of developing prediabetes and diabetes was higher in patients with OSA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.