Evidence map›Paper›PMID 35302456›Full record

Observational studyThe western journal of emergency medicine2022

Prehospital Translation of Chest Pain Tools (RESCUE Study): Completion Rate and Inter-rater Reliability.

Anna C Snavely, Simon A Mahler, Nella W Hendley, Nicklaus P Ashburn, Brian Hehl, Jordan Vorrie, Matthew Wells, R Darrel Nelson, Chadwick D Miller, Jason P Stopyra

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in The western journal of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Anna C SnavelyWake Forest School of Medicine, Department of Emergency Medicine, Winston-Salem, North Carolina.
Simon A MahlerWake Forest School of Medicine, Department of Emergency Medicine, Winston-Salem, North Carolina.
Nella W HendleyWake Forest School of Medicine, Department of Emergency Medicine, Winston-Salem, North Carolina.
Nicklaus P AshburnWake Forest School of Medicine, Department of Emergency Medicine, Winston-Salem, North Carolina.
Brian HehlCape Fear Valley Health, Department of Emergency Medicine, Fayetteville, North Carolina.
Jordan VorrieCape Fear Valley Health, Department of Emergency Medicine, Fayetteville, North Carolina.
Matthew WellsCape Fear Valley Health, Department of Emergency Medicine, Fayetteville, North Carolina.
R Darrel NelsonWake Forest School of Medicine, Department of Emergency Medicine, Winston-Salem, North Carolina.
Chadwick D MillerWake Forest School of Medicine, Department of Emergency Medicine, Winston-Salem, North Carolina.
Jason P StopyraWake Forest School of Medicine, Department of Emergency Medicine, Winston-Salem, North Carolina.
Wake Forest University · USFayetteville VA Medical Center · USCape Fear Valley Health System · USCape Fear Valley Medical Center · US

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
CVD Epidemiology Training ProgramT32HL076132 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DAVID McLeod HERRINGTON · 2004 to 2026
$8.4M
Wake Forest Clinical and Translational Science AwardKL2TR001421 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MILLER, DAVID P · 2015 to 2023
$5.8M
CMR-IMPACTR01HL118263 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MILLER, CHADWICK DAVID · 2013 to 2018
$3.7M
Wake Forest Clinical Center for the NHLBI PETAL NetworkU01HL123027 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI FILES, DANIEL CLARK, MILLER, CHADWICK DAVID · 2014 to 2020
$1.8M
NCATS NIH HHS KL2 TR001421NCATS NIH HHS UL1 TR001420NHLBI NIH HHS R01 HL118263NHLBI NIH HHS T32 HL076132NHLBI NIH HHS U01 HL123027
6 · The paper itself

Abstract

introductionChest pain is a common reason for ambulance transport. Acute coronary syndrome (ACS) and pulmonary embolism (PE) risk assessments, such as history, electrocardiogram, age, risk factors (HEAR); Emergency Department Assessment of Chest Pain Score (EDACS); Pulmonary Embolism Rule-out Criteria (PERC); and revised Geneva score, are well validated for emergency department (ED) use but have not been translated to the prehospital setting. The objectives of this study were to evaluate the 1) prehospital completion rate and 2) inter-rater reliability of chest pain risk assessments.

methodsWe conducted a prospective observational cohort study in two emergency medical services (EMS) agencies (April 18, 2018 - January 2, 2019). Adults with acute, non-traumatic chest pain without ST-elevation myocardial infarction or unstable vital signs were accrued. Paramedics were trained to use the HEAR, EDACS, PERC, and revised Geneva score assessments. A subset of patients (a priori goal of N = 250) also had the four risk assessments completed by their treating clinicians in the ED, who were blinded to the EMS risk assessments. Outcomes were 1) risk assessments completion rate and 2) inter-rater reliability between EMS and ED assessments. An a priori goal for completion rate was set as >75%. We computed kappa with corresponding 95% confidence intervals (CI) for each risk assessment as a measure of inter-rater reliability. Acceptable agreement was defined a priori as kappa ≥ 0.60.

resultsDuring the study period, 837 patients with acute chest pain were accrued. The median age was 54 years, interquartile range 43-66, with 53% female and 51% Black. Completion rates for each risk assessment were above goal: the HEAR score was completed on 95.1% (796/837), EDACS on 92.0% (770/837), PERC on 89.4% (748/837), and revised Geneva score on 90.7% (759/837) of patients. We assessed agreement in a subgroup of 260 patients. The HEAR score had a kappa of 0.51 (95% CI, 0.41-0.61); EDACS was 0.60 (95% CI, 0.49-0.72); PERC was 0.71 (95% CI, 0.61-0.81); and revised Geneva score was 0.51 (95% CI, 0.39-0.62).

conclusionThe completion rate of risk assessments for ACS and PE was high for prehospital field personnel. The PERC and EDACS both demonstrated acceptable agreement between paramedics and clinicians in the ED, although assessments with better agreement are likely needed.

Indexed as

Acute Coronary SyndromeEmergency Medical ServicesAdultChest PainFemaleHumansMaleMiddle AgedProspective StudiesReproducibility of Results

Identifiers

PMID35302456
PMCPMC8967468
OpenAlexW4214841900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.