Evidence map›Paper›PMID 35301981›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2022

Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021.

Paula B Blomquist, Jessica Bridgen, Neil Bray, Anne Marie O'Connell, Daniel West, Natalie Groves, Eileen Gallagher, Lara Utsi, Christopher I Jarvis, Jo L Hardstaff and 16 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Newer emerging SARS-COV2 variant: Omicron EG.5.Annals of medicine and surgery (2012) · 2023
    Article
  4. A standardised protocol for relative SARS-CoV-2 variant severity assessment, applied to Omicron BA.1 and Delta in six European countries, October 2021 to February 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Paula B BlomquistCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Jessica BridgenCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Neil BrayCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Anne Marie O'ConnellCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Daniel WestUK Health Security Agency, London, United Kingdom.
Natalie GrovesUK Health Security Agency, London, United Kingdom.
Eileen GallagherUK Health Security Agency, London, United Kingdom.
Lara UtsiCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Christopher I JarvisCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Jo L HardstaffCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Chloe ByersCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Soeren MetelmannCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
David SimonsCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Asad ZaidiUK Health Security Agency, London, United Kingdom.
Katherine A TwohigUK Health Security Agency, London, United Kingdom.
Bethan SavagarCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Alessandra LøchenCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Cian RyanCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Katie WrennCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
María Saavedra-CamposCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Zahidul AbedinCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Isaac FlorenceUK Health Security Agency, London, United Kingdom.
Paul ClearyCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Richard ElsonCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Roberto VivancosCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.
Iain R LakeCOVID-19 Outbreak Surveillance Team, UK Health Security Agency, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When SARS-CoV-2 Omicron emerged in 2021, S gene target failure enabled differentiation between Omicron and the dominant Delta variant. In England, where S gene target surveillance (SGTS) was already established, this led to rapid identification (within ca 3 days of sample collection) of possible Omicron cases, alongside real-time surveillance and modelling of Omicron growth. SGTS was key to public health action (including case identification and incident management), and we share applied insights on how and when to use SGTS.

Indexed as

COVID-19SARS-CoV-2HumansMembrane GlycoproteinsSpike Glycoprotein, CoronavirusViral Envelope ProteinsMembrane GlycoproteinsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Viral Envelope ProteinsCOVD-19disease surveillanceOmicronpublic healthSARS-CoV-2s-gene target failure

Identifiers

PMID35301981
PMCPMC8971917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.