Evidence map›Paper›PMID 35301900›Full record

ArticleThe Journal of international medical research2022

NF-kB pathway is involved in microscopic colitis pathogenesis.

Laura Francesca Pisani, Gianeugenio Tontini, Maurizio Vecchi, Giorgio Alberto Croci, Luca Pastorelli

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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  8. DNA methylation-mediatedFrontiers in molecular biosciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura Francesca PisaniGastroenterology and Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Italy.ORCID https://orcid.org/0000-0002-9490-3723
Gianeugenio TontiniDepartment of Medical-Surgical Physiopathology and Transplantation, Università degli Studi di Milano, Milano, Italy.
Maurizio VecchiDepartment of Medical-Surgical Physiopathology and Transplantation, Università degli Studi di Milano, Milano, Italy.
Giorgio Alberto CrociDepartment of Medical-Surgical Physiopathology and Transplantation, Università degli Studi di Milano, Milano, Italy.
Luca PastorelliGastroenterology and Liver Unit, 444273ASST Santi Paolo e Carlo, ASST Santi Paolo e Carlo, Milano, Italy.
University of Milan · ITIRCCS Policlinico San Donato · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the potential inflammatory pathways involved in the development of microscopic colitis (MC).

methodsThis prospective study analysed human intestinal tissue that was collected and classified as healthy controls (HC), microscopic colitis (MC) and ulcerative colitis (UC). An RT

resultsThis study measured the expression of inflammatory genes in HC (

conclusionsThe findings suggest that an impairment of the non-canonical NF-kB pathway is involved in the development of MC.

Indexed as

Colitis, MicroscopicColitis, UlcerativeNF-kappa BHumansIntestinesMetabolic Networks and PathwaysProspective StudiesNF-kappa Bcollagenous colitisinflammationinflammatory pathwaylymphocytic colitisMicroscopic colitis

Identifiers

PMID35301900
PMCPMC8935566
OpenAlexW4221056788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.