Evidence map›Paper›PMID 35301872›Full record

ArticleJournal of the American Heart Association2022

Demographic and Regional Trends of Mortality in Patients With Aortic Dissection in the United States, 1999 to 2019.

Salik Nazir, Robert W Ariss, Abdul Mannan Khan Minhas, Rochell Issa, Erin D Michos, Yochai Birnbaum, George V Moukarbel, P Kasi Ramanathan, Hani Jneid

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Observational
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  11. Aortic dissection mortality in the United States, 1968-2023: Trends, disparities, and deep learning forecasts.International journal of cardiology. Cardiovascular risk and prevention · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Salik NazirDivision of Cardiovascular Medicine University of Toledo Medical Center Toledo OH.ORCID 0000-0001-8202-9576
Robert W ArissDivision of Cardiovascular Medicine University of Toledo Medical Center Toledo OH.ORCID 0000-0001-5555-5829
Abdul Mannan Khan MinhasDivision of Medicine Forrest General Hospital Hattiesburg MS.ORCID 0000-0002-9829-3520
Rochell IssaDivision of Cardiovascular Medicine University of Toledo Medical Center Toledo OH.ORCID 0000-0003-4948-3210
Erin D MichosDivision of Cardiology Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0002-5547-5084
Yochai BirnbaumSection of Cardiology Baylor College of Medicine Houston TX.ORCID 0000-0001-7653-6328
George V MoukarbelDivision of Cardiovascular Medicine University of Toledo Medical Center Toledo OH.ORCID 0000-0001-9719-3854
P Kasi RamanathanSection of Cardiology ProMedica Toledo Hospital Toledo OH.
Hani JneidSection of Cardiology Baylor College of Medicine Houston TX.ORCID 0000-0002-8754-358X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Aortic dissection (AoD) is associated with high morbidity and mortality. However, the burden of AoD mortality is not well characterized, and contemporary data and mortality trends in different demographic and geographic subgroups have not been described. Methods and Results Trends in AoD mortality were assessed using a cross-sectional analysis of the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database. Crude and age-adjusted mortality rates (AAMR) per 1 million people with associated annual percent changes were determined. Joinpoint regression was used to assess trends in the overall sample and different demographic (sex, race and ethnicity, age) and geographic subgroups. Between 1999 and 2019, a total of 86 855 AoD deaths occurred within the United States. In the overall population, AAMR was 21.1 per 1 million in 1999 and 21.3 in 2019. After an initial decline in mortality, AAMR increased from 2012 to 2019, with an associated annual change of 2.5% (95% CI, 1.8-3.3). Men, older adults (aged ≥85 years), and non-Hispanic Black or African American individuals had higher mortality rates than women, younger individuals, and other racial and ethnic individuals, respectively. Despite lower AAMRs throughout the study period, women experienced greater increases in AAMR from 2012 to 2019 compared with men. Similarly, non-Hispanic Black or African American individuals had a pronounced increase in AAMR from 2012 to 2019. Conclusions Despite an initial decline in AoD mortality, the mortality rate has been increasing from 2012 to 2019, with pronounced increases among women and non-Hispanic Black or African American individuals.

Indexed as

Aortic DissectionBlack or African AmericanAgedAged, 80 and overBlack PeopleCross-Sectional StudiesEthnicityFemaleHumansMaleMortalityUnited Statesaortic dissectionepidemiologymortality

Identifiers

PMID35301872
PMCPMC9075427

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.